Pemphigus Vulgaris (PV) - Market Insights, Epidemiology and Market Forecast-2028

Pemphigus Vulgaris (PV) - Market Insights, Epidemiology and Market Forecast-2028 report delivers an in-depth understanding of the disease, historical & forecasted epidemiology as well as the market trends of Pemphigus Vulgaris (PV) in the United States, EU5 (Germany, Spain, Italy, France and United Kingdom), and Japan.
The Report provides the current treatment practices, emerging drugs, market share of the individual therapies, current and forecasted market size of Pemphigus Vulgaris from 2016 to 2028 segmented by seven major markets. The Report also covers current treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assess underlying potential of the market.

Geography Covered
The United States
EU5 (Germany, France, Italy, Spain and the United Kingdom)
Japan

Study Period: 2016-2028

Pemphigus Vulgaris (PV) - Disease Understanding and Treatment Algorithm
The PV market report gives the thorough understanding of PV by including details such as disease definition, classification, symptoms, etiology, pathophysiology, diagnostic trends. It also provides treatment algorithms and treatment guidelines for PV in the US, Europe, and Japan.

Pemphigus Vulgaris (PV) Epidemiology
The Pemphigus Vulgaris epidemiology division provide the insights about historical and current patient pool and forecasted trend for each of the 7 major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the report also provides the diagnosed patient pool and their trends along with assumptions undertaken.
The disease epidemiology covered in the report provides historical as well as forecasted epidemiology [total prevalent cases, prevalent cases by Severity (Mild, Moderate and Severe), diagnosed and treatable cases] of PV in the 7MM covering United States, EU5 countries (Germany, Spain, Italy, France and United Kingdom) and Japan from 2016-2028.
According to DelveInsight, total prevalent population of Pemphigus Vulgaris in 7 major markets was estimated to be 62,747 in 2016.

Pemphigus Vulgaris (PV) Drug Chapters
This segment of the Pemphigus Vulgaris report encloses the detailed analysis of marketed drugs and late stage (Phase-III and Phase-II) pipeline drugs. It also helps to understand the clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug and the latest news and press releases.
The current treatment approaches are aimed at controlling the disease rather than serving as a cure. . The treatment usually focuses on immune suppression and starts with a corticosteroid; often in combination with steroid-sparing drugs. Although Corticosteroid drugs have been proven to be very effective for this indication by reducing the mortality of several folds since last decade, the related long-term high toxicity hampers the quality of life of the patient. To overcome toxicity, severe side effects and complications of current treatment methods, many companies are developing potential therapies. Detailed chapter for upcoming therapies Rituximab (Hoffmann-La Roche), PRN1008 (Principia Biopharma Inc.), VAY736 (Novartis Pharmaceuticals) and ARGX-113 (Argenx) have been covered in the report.

Pemphigus Vulgaris (PV) Market Outlook
The PV market outlook of the report helps to build the detailed comprehension of the historic, current and forecasted trend of the market by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand of better technology.
This segment gives a through detail of market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on annual cost of therapy, inclusion and exclusion criterias, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated market data are presented with relevant tables and graphs to give a clear view of the market at first sight.
According to DelveInsight, the market of Pemphigus Vulgaris (PV) in 7MM was found to be USD 74.03 million in 2016, and is expected to increase at a CAGR of XX% from 2016-2028.

Pemphigus Vulgaris (PV) Drugs Uptake
This section focusses on the rate of uptake of the potential drugs recently launched in the market or will get launched in the market during the study period from 2016-2028. The analysis covers market uptake by drugs; patient uptake by therapies and sales of each drug.
This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allows the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

Pemphigus Vulgaris (PV) Report Insights
Patient Population
Therapeutic Approaches
Pipeline Analysis
Market Size and Trends
Market Opportunities
Impact of upcoming Therapies

Pemphigus Vulgaris (PV) Report Key Strengths
10 Year Forecast
7MM Coverage
Epidemiology Segmentation
Drugs Uptake
Highly Analyzed Market
Key Cross Competition

Pemphigus Vulgaris (PV) Report Assessment
Current Treatment Practices
Unmet Needs
Detailed Pipeline Product Profiles
Market Attractiveness
Market Drivers and Barriers

Key Benefits
This report will help to develop Business Strategies by understanding the trends shaping and driving Pemphigus Vulgaris (PV) market
Organize sales and marketing efforts by identifying the best opportunities for Pemphigus Vulgaris (PV) market
To understand the future market competition in the Pemphigus Vulgaris (PV) market.

1. Key Insights
2. Pemphigus Vulgaris Market Overview at a Glance
2.1. Market Share (%) Distribution of Pemphigus Vulgaris in 2016
2.2. Market Share (%) Distribution of Pemphigus Vulgaris in 2028
3. Disease Background and Overview: Pemphigus Vulgaris (PV)
3.1. Introduction
3.2. Clinical manifestations
3.3. Disease Causes
3.4. PV-Symptoms
3.5. Pathophysiology
3.6. PV Diagnosis
3.6.1. Diagnosis of Pemphigus Vulgaris: Recommendations by an International Panel of Experts
4. Epidemiology and Patient Population
4.1. Key Findings
4.2. Disease Definition
4.3. Population and Forecast Parameters
4.4. 7MM Prevalent Population of Pemphigus Vulgaris (PV)
4.5. 7MM Prevalent Population of PV by Severity
5. Country Wise-Epidemiology of Pemphigus Vulgaris (PV)
5.1. United States
5.1.1. Prevalent cases of PV in the United States
5.1.2. Prevalent cases of PV by severity in the United States
5.1.3. Diagnosed cases of PV in the United States
5.1.4. Treatable cases of PV in the United States
5.2. Germany
5.2.1. Prevalent cases of PV in Germany
5.2.2. Prevalent cases of PV by severity in Germany
5.2.3. Diagnosed cases of PV in Germany
5.2.4. Treatable cases of PV in Germany
5.3. France
5.3.1. Prevalent cases of PV in France
5.3.2. Prevalent cases of PV by severity in France
5.3.3. Diagnosed cases of PV in France
5.3.4. Treatable cases of PV in France
5.4. Italy
5.4.1. Prevalent cases of PV in Italy
5.4.2. Prevalent cases of PV by severity in Italy
5.4.3. Diagnosed cases of PV in Italy
5.4.4. Treatable cases of PV in Italy
5.5. Spain
5.5.1. Prevalent cases of PV in Spain
5.5.2. Prevalent cases of PV by severity in Spain
5.5.3. Diagnosed cases of PV in Spain
5.5.4. Treatable cases of PV in Spain
5.6. United Kingdom
5.6.1. Prevalent cases of PV in the UK
5.6.2. Prevalent cases of PV by severity in the UK
5.6.3. Diagnosed cases of PV in the UK
5.6.4. Treatable cases of PV in the UK
5.7. Japan
5.7.1. Prevalent cases of PV in Japan
5.7.2. Prevalent cases of PV by severity in Japan
5.7.3. Diagnosed cases of PV in Japan
5.7.4. Treatable cases of PV in Japan
6. Treatment Algorithm
6.1. Treatment of Pemphigus Vulgaris: Recommendations by an International Panel of Experts
6.2. British Association of Dermatologists Guidelines for management of Pemphigus Vulgaris, 2016
6.3. Treatment Strategies for Pemphigus Vulgaris in Japan
7. Unmet needs
8. Emerging Therapies
8.1. Key Cross Competition
8.2. Phase II Drugs
8.3. ARGX-113: Argenx
8.3.1. Drug Description
8.3.2. Product Profile
8.3.3. Other development activities
8.3.4. Clinical Development
8.3.5. Clinical Trials Information
8.4. PRN1008: Principia Biopharma, Inc.
8.4.1. Drug Description
8.4.2. Product Profile
8.4.3. Regulatory milestones
8.4.4. Other Development Activities
8.4.5. Clinical Development
8.4.6. Clinical Trials Information
8.4.7. Safety and Efficacy
8.5. Rituximab (RG 105): Hoffmann-La Roche
8.5.1. Drug Description
8.5.2. Product Profile
8.5.3. Regulatory milestones
8.5.4. Other Development Activities
8.5.5. Clinical Development
8.5.6. Clinical Trials Information
8.6. VAY736: Novartis Pharmaceuticals
8.6.1. Drug Description
8.6.2. Product Profile
8.6.3. Regulatory milestones
8.6.4. Clinical Development
8.6.5. Clinical Trials Information
9. Discontinued Drug
9.1. Ofatumumab: Novartis Pharmaceuticals
9.1.1. Drug Description
9.1.2. Product Profile
9.1.3. Other development activities
9.1.4. Clinical Development
9.1.5. Clinical Trials Information
10. Inactive Drug
10.1. KC 706: Kmia Drug Description
10.1.1. Product Profile
10.1.2. Clinical Development
10.1.3. Clinical Trials Information
11. Pemphigus Vulgaris: Market Analysis
11.1. Key Findings
11.2. Pemphigus Vulgaris: Total Market Size in 7MM
11.3. Total Market Size of Pemphigus Vulgaris in 7MM
11.4. Therapy Based PV Market by Severity in 7MM
11.5. Therapy Based PV Market of Mild Cases in 7MM
11.6. Therapy Based PV Market of Moderate Cases in 7MM
11.7. Therapy Based PV Market of Severe Cases in 7MM
12. Market Size of Pemphigus Vulgaris by Country
12.1. United States Market Analysis
12.1.1. Market Size of Pemphigus Vulgaris in the US
12.1.2. Therapy Based PV Market of Mild Cases in the US
12.1.3. Therapy Based PV Market of Moderate Cases in the US
12.1.4. Therapy Based PV Market of Severe Cases in the US
12.2. Pemphigus Vulgaris: EU5 Market Outlook
12.3. Germany
12.3.1. Market Size of Pemphigus Vulgaris in Germany
12.3.2. Therapy Based PV Market of Mild Cases in Germany
12.3.3. Therapy Based PV Market of Moderate Cases in Germany
12.3.4. Therapy Based PV Market of Severe Cases in Germany
12.4. France
12.4.1. Market Size of Pemphigus Vulgaris in France
12.4.2. Therapy Based PV Market of Mild Cases in France
12.4.3. Therapy Based PV Market of Moderate Cases in France
12.4.4. Therapy Based PV Market of Severe Cases in France
12.5. Italy
12.5.1. Market Size of Pemphigus Vulgaris in Italy
12.5.2. Therapy Based PV Market of Mild Cases in Italy
12.5.3. Therapy Based PV Market of Moderate Cases in Italy
12.5.4. Therapy Based PV Market of Severe Cases in Italy
12.6. Spain
12.6.1. Market Size of Pemphigus Vulgaris in Spain
12.6.2. Therapy Based PV Market of Mild Cases in Spain
12.6.3. Therapy Based PV Market of Moderate Cases in Spain
12.6.4. Therapy Based PV Market of Severe Cases in Spain
12.7. United Kingdom
12.7.1. Market Size of Pemphigus Vulgaris in the UK
12.7.2. Therapy Based PV Market of Mild Cases in the UK
12.7.3. Therapy Based PV Market of Moderate Cases in the UK
12.7.4. Therapy Based PV Market of Severe Cases in the UK
12.8. Japan: Market Analysis
12.8.1. Market Size of Pemphigus Vulgaris in Japan
12.8.2. Therapy Based PV Market of Mild Cases in Japan
12.8.3. Therapy Based PV Market of Moderate Cases in Japan
12.8.4. Therapy Based PV Market of Severe Cases in Japan
13. Market Drivers of PV
14. Market Barriers of PV
15. Appendix
16. Report Methodology
16.1. Sources Used
17. DelveInsight Capabilities
18. Disclaimer
19. About DelveInsight

List Of Tables

Table 1: Drugs associated with Pemphigus Vulgaris (PV)
Table 2: Differential diagnosis of oral lesions in PV
Table 3: Prevalent Population of PV in the 7MM (2016-2028)
Table 4: 7MM Prevalent Population of PV by severity(2016-2028)
Table 5: Prevalent Cases of PV in the United States (2016-2028)
Table 6: Prevalent Cases of PV in the United States (2016-2028)
Table 7: Diagnosed cases of PV and its Types in the United States (2016-2028)
Table 8: Treatable cases of PV in the United States (2016-2028)
Table 9: Prevalent Cases of PV in Germany (2016-2028)
Table 10: Prevalent Cases of PV by severity in Germany (2016-2028)
Table 11: Diagnosed cases of PV in Germany (2016-2028)
Table 12: Treatable cases of PV in Germany (2016-2028)
Table 13: Prevalent Cases of PV in France (2016-2028)
Table 14: Prevalent Cases of PV by severity in France (2016-2028)
Table 15: Diagnosed cases of PV in France (2016-2028)
Table 16: Treatable cases of PV in France (2016-2028)
Table 17: Prevalent Cases of PV in Italy (2016-2028)
Table 18: Prevalent Cases of PV by severity in Italy (2016-2028)
Table 19: Diagnosed cases of PV in Italy (2016-2028)
Table 20: Treatable cases of PV in Italy (2016-2028)
Table 21: Prevalent Cases of PV in Spain (2016-2028)
Table 22: Prevalent Cases of PV by severity in Spain (2016-2028)
Table 23: Diagnosed cases of PV in Spain (2016-2028)
Table 24: Treatable cases of PV in Spain (2016-2028)
Table 25: Prevalent Cases of PV in the UK (2016-2028)
Table 26: Prevalent Cases of PV by severity in the UK (2016-2028)
Table 27: Diagnosed cases of PV in the UK (2016-2028)
Table 28: Treatable cases of PV in the UK (2016-2028)
Table 29: Prevalent Cases of PV in Japan (2016-2028)
Table 30: Prevalent Cases of PV by severity in Japan (2016-2028)
Table 31: Diagnosed cases of PV in Japan (2016-2028)
Table 32: Treatable cases of PV in Japan (2016-2028)
Table 33: Medication Dosing
Table 34: Overview of Management of Pemphigus Vulgaris
Table 35: Management of Pemphigus Vulgaris
Table 34: ARGX-113, Clinical Trial Description, 2016
Table 35: PRN1008, Clinical Trial Description, 2016
Table 36: Rituximab, Clinical Trial Description, 2016
Table 36: VAY 736, Clinical Trial Description, 2016
Table 36: Ofatumumab, Clinical Trial Description, 2016
Table 36: KC706, Clinical Trial Description, 2016
Table 42: 7MM Major Market Size of Pemphigus Vulgaris in USD Million (2016-2028)
Table 43: Therapy Based PV Market of Mild Cases in 7MM in USD Million (2016-2028)
Table 44: Therapy Based PV Market of Moderate Cases in 7MM in USD Million (2016-2028)
Table 45: Therapy Based PV Market of Severe Cases in 7MM in USD Million (2016-2028)
Table 46: Market Size of PV in the US, USD Million (2016-2028)
Table 47: Therapy Based PV Market of Mild Cases in the US in USD Million (2016-2028)
Table 48: Therapy Based PV Market of Moderate Cases in the US in USD Million (2016-2028)
Table 49: Therapy Based PV Market of Severe Cases in the US in USD Million (2016-2028)
Table 50: Market Size of PV in Germany, USD Million (2016-2028)
Table 51: Therapy Based PV Market of Mild Cases in Germany in USD Million (2016-2028)
Table 52: Therapy Based PV Market of Moderate Cases in Germany in USD Million (2016-2028)
Table 53: Therapy Based PV Market of Severe Cases in Germany in USD Million (2016-2028)
Table 54: Market Size of Pemphigus Vulgaris in France in USD Million (2016-2028)
Table 55: Therapy Based PV Market of Mild Cases in France in USD Million (2016-2028)
Table 56: Therapy Based PV Market of Moderate Cases in France in USD Million (2016-2028)
Table 57: Therapy Based PV Market of Severe Cases in France in USD Million (2016-2028)
Table 58: Market Size of Pemphigus Vulgaris in Italy, USD Million (2016-2028)
Table 59: Therapy Based PV Market of Mild Cases in Italy in USD Million (2016-2028)
Table 60: Therapy Based PV Market of Moderate Cases in Italy in USD Million (2016-2028)
Table 61: Therapy Based PV Market of Severe Cases in Italy in USD Million (2016-2028)
Table 62: Market Size of Pemphigus Vulgaris in Spain, USD Million (2016-2028)
Table 63: Therapy Based PV Market of Mild Cases in Spain in USD Million (2016-2028)
Table 64: Therapy Based PV Market of Moderate Cases in Spain in USD Million (2016-2028)
Table 65: Therapy Based PV Market of Severe Cases in Spain in USD Million (2016-2028)
Table 66: Market Size of Pemphigus Vulgaris in the UK, USD Million (2016-2028)
Table 67: Therapy Based PV Market of Mild Cases in the UK in USD Million (2016-2028)
Table 68: Therapy Based PV Market of Moderate Cases in the UK in USD Million (2016-2028)
Table 69: Therapy Based PV Market of Severe Cases in the UK in USD Million (2016-2028)
Table 70: Japan Market Size of Pemphigus Vulgaris in USD Million (2016-2028)
Table 71: Therapy Based PV Market of Mild Cases in Japan in USD Million (2016-2028)
Table 72: Therapy Based PV Market of Moderate Cases in Japan in USD Million (2016-2028)
Table 73: Therapy Based PV Market of Severe Cases in Japan in USD Million (2016-2028)

List Of Figures

Figure 1: Clinical manifestations of Pemphigus
Figure 2: Pathogenesis of Pemphigus
Figure 3: Mechanisms of Acantholysis
Figure 4: B-cell and T-cell responses in Pemphigus
Figure 5: A multistep approach for diagnosing PV
Figure 6: Pemphigus Area and Activity Score
Figure 7: PEmphigus Activity Score
Figure 8: Pemphigus Disease Area Index
Figure 9: Pemphigus Vulgaris Lesion Severity Score
Figure 10: Harmans Pemphigus Grading
Figure 11: Kumars Scoring System
Figure 12: Mahajans Scoring System
Figure 13: Diagnostic Recommendations for PV by International Panel of Experts
Figure 14: Prevalent Population of PV in 7MM (2016-2028)
Figure 15: 7MM Prevalent Population of PV by severity (2016-2028)
Figure 16: Prevalent cases of PV in the United States (2016-2028)
Figure 17: Prevalent cases of PV by severity in the United States (2016-2028)
Figure 18: Diagnosed Cases of PV in the United States (2016-2028)
Figure 19: Treatable cases of PV in the United States (2016-2028)
Figure 20: Prevalent cases of PV in Germany (2016-2028)
Figure 21: Prevalent cases of PV by severity in Germany (2016-2028)
Figure 22: Diagnosed Cases of PV in Germany (2016-2028)
Figure 23: Treatable cases of PV in Germany (2016-2028)
Figure 24: Prevalent cases of PV in France (2016-2028)
Figure 25: Prevalent cases of PV by severity in France (2016-2028)
Figure 26: Diagnosed Cases of PV in France (2016-2028)
Figure 27: Treatable cases of PV in France (2016-2028)
Figure 28: Prevalent cases of PV in Italy (2016-2028)
Figure 29: Prevalent cases of PV by severity in Italy (2016-2028)
Figure 30: Diagnosed Cases of PV in Italy (2016-2028)
Figure 31: Treatable cases of PV in Italy (2016-2028)
Figure 32: Prevalent cases of PV in Spain (2016-2028)
Figure 33: Prevalent cases of PV by severity in Spain (2016-2028)
Figure 34: Diagnosed Cases of PV in Spain (2016-2028)
Figure 35: Treatable cases of PV in Spain (2016-2028)
Figure 36: Prevalent cases of PV in the UK (2016-2028)
Figure 37: Prevalent cases of PV by severity in the UK (2016-2028)
Figure 38: Diagnosed Cases of PV in the UK (2016-2028)
Figure 39: Treatable cases of PV in the UK (2016-2028)
Figure 40: Prevalent cases of PV in Japan (2016-2028)
Figure 41: Prevalent cases of PV by severity in Japan (2016-2028)
Figure 42: Diagnosed Cases of PV in Japan (2016-2028)
Figure 43: Treatable cases of PV in Japan (2016-2028)
Figure 44: Treatment Algorithm of PV
Figure 45: Treatment Recommendations for PV By International Panel of Experts
Figure 46: Algorithm to treat patients with PV
Figure 47: Unmet needs of PV
Figure 48: 7MM Market Size of Pemphigus Vulgaris in USD Million (2016-2028)
Figure 49: Therapy Based PV Market of Mild cases in 7MM in USD Million (2016-2028)
Figure 50: Therapy Based PV Market of Moderate cases in 7MM in USD Million (2016-2028)
Figure 51: Therapy Based PV Market of Severe cases in 7MM in USD Million (2016-2028)
Figure 52: Market Size of PV in the US, USD Million (2016-2028)
Figure 53: Therapy Based PV Market of Mild cases in the US in USD Million (2016-2028)
Figure 54: Therapy Based PV Market of Moderate cases in the US in USD Million (2016-2028)
Figure 55: Therapy Based PV Market of Severe cases in the US in USD Million (2016-2028)
Figure 56: Market Size of PV in Germany, USD Million (2016-2028)
Figure 57: Therapy Based PV Market of Mild cases in Germany in USD Million (2016-2028)
Figure 58: Therapy Based PV Market of Moderate cases in Germany in USD Million (2016-2028)
Figure 59: Therapy Based PV Market of Severe cases in Germany in USD Million (2016-2028)
Figure 60: Market Size of PV in France, USD Million (2016-2028)
Figure 61: Therapy Based PV Market of Mild cases in France in USD Million (2016-2028)
Figure 62: Therapy Based PV Market of Moderate cases in France in USD Million (2016-2028)
Figure 63: Therapy Based PV Market of Severe cases in France in USD Million (2016-2028)
Figure 64: Market Size of PV in Italy, USD Million (2016-2028)
Figure 65: Therapy Based PV Market of Mild cases in Italy in USD Million (2016-2028)
Figure 66: Therapy Based PV Market of Moderate cases in Italy in USD Million (2016-2028)
Figure 67: Therapy Based PV Market of Severe cases in Italy in USD Million (2016-2028)
Figure 68: Market Size of PV in Spain, USD Million (2016-2028)
Figure 69: Therapy Based PV Market of Mild cases in Spain in USD Million (2016-2028)
Figure 70: Therapy Based PV Market of Moderate cases in Spain in USD Million (2016-2028)
Figure 71: Therapy Based PV Market of Severe cases in Spain in USD Million (2016-2028)
Figure 72: Market Size of PV in the UK, USD Million (2016-2028)
Figure 73: Therapy Based PV Market of Mild cases in the UK in USD Million (2016-2028)
Figure 74: Therapy Based PV Market of Moderate cases in the UK in USD Million (2016-2028)
Figure 75: Therapy Based PV Market of Severe cases in the UK in USD Million (2016-2028)
Figure 76: Market Size of PV in Japan, USD Million (2016-2028)
Figure 77: Therapy Based PV Market of Mild cases in Japan in USD Million (2016-2028)
Figure 78: Therapy Based PV Market of Moderate cases in Japan in USD Million (2016-2028)
Figure 79: Therapy Based PV Market of Severe cases in Japan in USD Million (2016-2028)
Figure 80: Market Drivers of PV
Figure 81: Market Barriers of PV

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