Emerging Nucleic Acid Testing (NAT) Assays, Country Market Shares, Strategic Profiles of Leading Reagent and Instrument Suppliers, 2019

This 549-page report presents an overview of the clinical significance and market needs for major current and emerging NAT assays, as well as extensive listings of companies developing and marketing innovative technologies and products.

This report also presents strategic assessments of current and emerging suppliers of nucleic acid testing products, including their sales, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies.

Microbiology/Infectious Diseases
a. Overview
b. Major Infectious Diseases
* AIDS
O Structure and Composition
O Classification
O AIDS Origins
O Animal Lentivirus Systems
O Virus Receptors
O HIV Infections in Humans
- Pathogenesis and Pathology
O CD4T Lymphocytes and Memory Cells
O Monocytes and Macrophages
O Lymphoid Organs
O Neural Cells
O Viral Coinfections
- Clinical Findings
O Plasma Viral Load
O Pediatric AIDS
- Neurologic Disease
- Opportunistic Infections
- Cancer
O Immunity
- Virus Isolation
- Serology
- Viral Nucleic Acid/Antigen Detection
O Epidemiology
- Worldwide Spread of AIDS
- United States
- Routes of Transmission

O DNA Probes
- Overview
- Quantitative PCR
- In Situ PCR
- Needed Improvements
O Viral Load/Drug Resistance Testing
O Genotype and Phenotype Testing
O Blood Banking Considerations
* Adenovirus
O Background
O Diagnostic Tests
O Vaccines and Drugs
O Adeno-Associated Viruses (AAV)
* Anthrax/Bacillus Anthracis
O Background
O Diagnostic Tests
O Vaccines and Drugs
* Babesiosis
O Background
* BEA and Other Bartonella Diseases
O Background
O Diagnostic Tests
O Vaccines and Drugs
* Chagas Disease
O Background
* Campylobacter
O Background
O Diagnostic Tests
- Culture Identification
O Vaccines and Drugs
* Chlamydia
O Background
- Chlamydia psittaci
- Chlmaydia pneumoniae
- Chlamydia trachomatis
O Diagnostic Tests
O Vaccines and Drugs
* Creutzfeldt-Jakobs Disease
O Background
O Blood Transmission
O Diagnostic Tests

O Major Commercial and Academic Players
- Bayer
- Disease Sciences/Bio Tec Global
- Imperial College School of Medicine
- Ortho-Clinical Diagnostics
- Pall
- ProMetic Life Sciences
- Proteome Sciences/Idexx
- Q-One Biotech
- Serono
- U.S. Agricultural Research Service
O Drugs
O Vaccines
* Cytomegalovirus
O Background
- Chorioretinitis
- Gastrointestinal
- Central Nervous System Disease
O Diagnostic Tests
O Vaccines and Drugs
* Ebola Virus
O Background
- Epidemiology
- Clinical Syndromes
O Diagnostic Tests
O Vaccines and Drugs
* EchoVirus
O Background
- Acute Aseptic Meningitisis
- Encephalitis
- Exanthems
- Respiratory Disease
- Myopericarditis
- Neonatal Infections
O Diagnostic Tests
O Vaccines and Drugs
* Encephalitis
O Background
O Diagnostic Tests
O Vaccines and Drugs

* Enteroviruses
O Background
O Diagnostic Tests
- Viral Isolation and Identification
- Antibody Tests
O Vaccines and Drugs
* Epstein-Barr Virus
O Background
O Diagnostic Tests
O Vaccines and Drugs
* Gonorrhea
O Background
O Diagnostic Tests
O Vaccines and Drugs
* Hepatitis
O Hepatitis A
O Hepatitis B
- Structure and Composition
- Replication
O Hepatitis C
O Hepatitis D (Delta)
O Hepatitis E
O Hepatitis G
O Hepatitis Infections Pathology
O Clinical Findings
O Laboratory Tests
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis D
- Hepatitis E
O Virus-Host Immune Reactions
O Epidemiology
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis D (Delta)
O Vaccines and Drugs

* Herpes Simplex Virus
O Background
O Diagnostic Tests
O Vaccines and Drugs
* Legionella
O Background
O Diagnostic Tests
O Vaccines and Drugs
* Lyme Disease
O Background
- Clinical Description
- Clinical Case Definition
- Laboratory Criteria for Diagnosis
- Case Classification
O Diagnostic Tests
O Vaccines and Drugs
* Malaria
* Mycoplasma
O Background
- Ureaplasma Urealyticum & Mycoplasma Hominis
O Diagnostic Tests
O Vaccines and Drugs
* Papillomaviruses/HPV
O Background
- HPV in Cancer
- Cervical Neoplasm
O Diagnostic Tests
O Vaccines and Drugs
- Prevention
* Parvovirus B19
O Background
- Microbiology
- Epidemiology
- Clinical Syndromes
- Erythema Infectiosum (Slapped Cheek)
- Adult Polyarthropathy
- Transient Aplastic Crisis
- Transient Pancytopenia

- Red Cell Aplasia in Immunocompromised
- Perinatal Infections
O Diagnostic Test
O Vaccines and Drugs
* Pneumonia
O Background
O Diagnostic Tests
O Vaccines and Drugs
* Polyomaviruses
O Background
O Diagnostic Tests
O Vaccines and Drugs
* Salmonellosis
O Background
O Diagnostic Tests
O Vaccines and Drugs
* Shigellosis
O Background
O Diagnostic Tests
O Vaccines and Drugs
* Streptococci
O Background
O Diagnostic Tests
O Vaccines and Drugs
- Group A Streptococci
- Group B Streptococci
* Toxoplasmosis
O Background
O Diagnostic Tests
O Vaccines and Drugs
* Tuberculosis
O Background
O Diagnostic Tests
- Microscopic Characteristics
- Cultural Characteristics
- Skin Tests
- MDRTB
O Vaccines and Drugs

* West Nile Virus
O Background
- Clinical Syndromes
O Diagnostic Tests
O Vaccines and Drugs
* Yersinia
O Background
O Diagnostic Tests
O Vaccines and Drugs
* Antibiotic Susceptibility
Cancer Testing
a. Overview
b. Major Cancer Types
* Prostate
* Lung
* Colon and Rectum
* Breast
* Skin
* Uterine
* Leukemia
* Oral
c. Oncogenes
O Abl/abl-bcr
O AIB1
O BCL-2
O BRCA1
O CD44
O C-fos
O C-myb
O C-myc
O CYP17
O Erb-B
O HPC1
O N-myc
O P40
O P51
O P53
O PIK3CA

O PTI-1
O Ras
O Reg
O Sis
O Src
Genetic Diseases
a. Overview
b. Nucleic Acid Amplification
c. Chromosome Imaging
d. Genomics Technologies
e. Proteomics Technologies
f. Current Pharmacogenomic Tests
g. Future Pharmacogenomic Testing
h. Major Diseases
* Achondroplasia
* Autosomal Dominant Polycystic Kidney Disease
* Cancer
* Cosmetogenomics
* Cystic Fibrosis
* Downs Syndrome
* Duchenne and Becker Muscular Dystrophy
* Factor V (Leiden)
* Factor IX Deficiency
* Fragile X Syndrome
* Heart Disease
* Hemochomatosis
* Hemophilia
* Huntingtons Disease
* Maternal-Fetal Incompatibility
* Multiple Endocrine Neoplasia
* Phenylketonuria (PKU)
* Polycystic Kidney Disease (PKD)
* Prenatal Screening
* Retinitis Pigmentosa
* Retinoblastoma
* Sickle Cell Anemia

* Spinal Muscular Atrophy
* Vitamin B12 Metabolism
i. Social Issues and Concerns
Forensic Testing
a. Overview
b. Multilocus and Single Locus Probes
* Multilocus Probes
* Single Locus Probes
* PCR and RFLP
c. The FBI
d. DNA Profile Data Banks
* U.S.A.
* U.K.
e. Judicial Implementation
f. Major Crime Categories
g. Factors Contributing to the DNA Probe Market Expansion
* Technology Availability
* Use of Hair as Evidence
h. Wildlife Forensics
Paternity Testing/HLA Typing
Other Applications
a. Disease Susceptibility Testing
b. Cardiovascular Diseases
c. Diabetes
d. Alzheimers Disease
e. Periodontal Disease
f. Plasma Purification
g. Organ Transplantation
h. Water Contamination
i. Other
Competitive Profiles

- Abbott
- Affymetrix
- Agilent Technologies
- Applied Gene Technologies
- Arca Biopharma
- Beckman Coulter/Danaher

- Becton Dickinson
- Biokit
- BioMerieux
- Bio-Rad
- Biotest
- Cepheid
- CellMark Forensics/LabCorp
- Decode Genetics
- Diadexus
- Elitech Group
- Eiken
- Enzo
- Exact Sciences
- Fujirebio
- Grifols
- Hologic/Gen-Probe
- Illumina
- Kreatech/Leica
- Li-Cor Biosciences
- Monogram Biosciences
- Myriad Genetics
- Ortho-Clinical Diagnostics
- Perkin Elmer/Caliper
- Proteome Sciences
- Qiagen
- Roche
- Scienion
- Sequenom
- Shimadzu
- Siemens
- Sierra Molecular
- Takara Bio
- Tecan Group
- Thermo Fisher

List Of Tables

Major Companies Developing or Marketing AIDS Molecular
Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Adenovirus
Molecular Diagnostic And Other Direct
Identification Tests
Major Companies Developing or Marketing Campylobacter
Molecular Diagnostic And Other Direct
Identification Tests
Major Companies Developing or Marketing Chlamydia
Molecular Diagnostic And Other Direct
Identification Tests
Major Companies Developing or Marketing CMV Molecular
Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing EBV Molecular
Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Gonorrhea
Molecular Diagnostic And Other Direct
Identification Tests
Major Companies Developing or Marketing Hepatitis
Molecular Diagnostic And Other Direct
Identification Tests
Major Companies Developing or Marketing Herpes
Molecular Diagnostic And Other Direct
Identification Tests
Major Companies Developing or Marketing Legionella
Molecular Diagnostic And Other Direct
Identification Tests

Major Companies Developing or Marketing Lyme
Disease Molecular Diagnostic And Other Direct
Identification Tests
Major Companies Developing or Marketing Mycoplasma
Molecular Diagnostic And Other Direct
Identification Tests
Major Companies Developing or Marketing Papilloma
Virus Molecular Diagnostic And Other Direct
Identification Tests
Major Companies Developing or Marketing Pneumonia
Molecular Diagnostic And Other Direct
Identification Tests
Major Companies Developing or Marketing Salmonella
Molecular Diagnostic And Other Direct
Identification Tests
Major Companies Developing or Marketing Shigella
Molecular Diagnostic And Other Direct
Identification Tests
Major Companies Developing or Marketing Streptococci
Molecular Diagnostic And Other Direct
Identification Tests
Major Companies Developing or Marketing Toxoplasmosis
Molecular Diagnostic And Other Direct
Identification Tests
Major Companies Developing or Marketing Tuberculosis
Molecular Diagnostic And Other Direct
Identification Tests

Oncogenes Potential Application in Cancer Diagnosis
Major Companies Developing or Marketing Cancer
Molecular Diagnostic Tests
Major Companies Developing or Marketing Molecular
Diagnostic Test For Genetic Diseases

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