2019-2023 Europe Molecular Diagnostic Analyzers and Reagents: Emerging Opportunities in France, Germany, Italy, Spain, UK--Infectious and Genetic Diseases, Cancer, Forensic and Paternity Testing--Supplier Shares, Volume and Sales Segment Forecasts, Emerging Technologies, Instrumentation Review

Complete report $19,700.  DataPack (test volumes, sales forecasts, supplier shares) $12,800.

This new 1,273-page comprehensive five-country report is designed to help current suppliers and potential market entrants identify and evaluate the major business opportunities emerging in the European molecular diagnostics market during the next five years. The report explores business and technological trends in major European countries (France, Germany, Italy, Spain, UK); provides 5-year test volume/sales forecasts; estimates shares of leading competitors; compares features of major analyzers; profiles leading market players; and identifies specific product and business opportunities facing instrument and consumable suppliers during the next five years.

The $4.5 billion molecular diagnostics market is unquestionably the most rapidly growing segment of the in vitro diagnostics industry. The next five years will witness significant developments in reagent systems and automation, as well as introduction of a wide range of new products that will require innovative marketing approaches. The rate of market penetration into routine clinical laboratories, however, will depend on the introduction of and cost-effective automated systems with amplification methods.

In order to successfully capitalize on the opportunities presented by the molecular diagnostics market, many companies are already exploiting new technologies as corporate strategic assets, managed in support of business and marketing strategies. Integrating new technology planning with business and corporate strategies will be one of the most challenging tasks for diagnostics companies during the next five years.  

Table of Contents

I.       Introduction

II.      Worldwide Technology and Market Overview

          A.  DNA Sequencing
             
          B.  DNA and RNA Probes Technology
             
          C.  Detection Technologies
             
          D.  Instrumentation Review
                        
          E.  Biochips: Genosensors, Microarrays, and Labs-on-the-Chip

          F.  Pharmacogenomics

          G.  Major Applications

III.     France

IV.     Germany

V.      Italy

VI.     Spain

VII.    U.K.

VIII.   Major Product Development Opportunities

IX.     Design Criteria for Decentralized Testing Products

X.      Alternative Market Penetration Strategies

XI.     Potential Market Entry Barriers and Risks

XII.    Competitive Assessments

XIII.   Appendix
                                                                                            

I. Introduction
II. Major Product Development Opportunities
A. Instrumentation
B. Reagent Kits and Test Systems/panels
C. Computers, Software and Automation
D. Auxiliary Products
III. Design Criteria for Decentralized Testing Products
IV. Alternative Market Penetration Strategies
A. Internal Development
B. Collaborative Arrangements
C. University Contracts
D. Distribution Strategies For Decentralized Testing
Markets
V. Potential Market Entry Barriers and Risks
A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge And Limitations
E. Patent Protection
F. Regulatory Constraints
G. Decentralized Testing Market Challenges
VI. Worldwide Market and Technology Review
A. DNA Sequencing
1. Introduction
2. Sequencing Methods
3. Autoradiography
4. The Human Genome Project
5. Sequencing Automation
Table of Contents (continued)
6. Image Scanners
7. Fluorescent Detection
8. Gene Profiling
9. Gene Expression
10. Polymorphism Screening
11. Protein Interaction Networks
B. DNA and RNA Probe Technologies
1. Basic Principles
2. Probe Preparation
3. The DNA Probe Test
4. Test Formats
5. Labeling Techniques
6. Amplification Methods
C. Detection Technologies
1. Radioactive Methods
a. Overview
b. Major Isotopes
O P-32
O S-35
O H-3
O I-125
2. Non-Isotopic Methods
a. Enzymatic Labels
b. Chemical Labeling
O Indirect Chemical Labeling
O Direct Chemical Labeling
c. Fluorescence
d. Chemiluminescence
e. Electrical Conductivity
D. Molecular Diagnostic Instrumentation Review
1. Abbott LCx
2. Beckman Coulter/Biomek FK
3. BD Viper System with XTR Technology
4. BD Innova
5. Becton Dickinson SDA
Table of Contents (continued)
6. bioMerieux NucliSENS easyMAG
7. bioMerieux NucliSENS easyQ and MiniMAG
8. Bio-Rad GeneScope
9. Cepheid GeneXpert
10. Curetis Unyvero
11. GenMark Dx eSensor XT-8
12. Hologic/Gen-Probe Panther
13. Hologic/Gen-Probe Tigris/DTS
14. HTG Molecular Edge
15. Life Technologies QuantStudio Dx
16. Qiagen QIAsymphony RGQ
17. Roche Cobas Amplicor
18. Roche Cobas TaqMan 48
19. Roche Cobas TaqMan
20. Roche Cobas TaqMan AmpliPrep
21. Roche LighCycler 480
22. Roche Cobas 4800
23. Roche Cobas s 201
24. Siemens Versant
25. Tecan LS Series
E. Biochips: Genosensors, Microarrays, and Labs-on-the-Chip
- Liquid Transportation and Mixing
- Separation
- Reaction
- Detection
F. Pharmacogenomics
G. Major Applications
1. Microbiology/Infectious Diseases
a. Overview
b. Major Infectious Diseases
AIDS: HIV/HIV-1/2/Combo, HIVAg/HIV NAT,
Western Blot, HTLV-I/II
Adenovirus
Aeromonas
Anthrax/Bacillus Anthracis
Table of Contents (continued)
Arboviruses
Babesiosis
Bacillary Epithelioid Angiomatosis (BEA)
and Other Bartonella (Rochalimaea)
Blastocystis Hominis
Brucella
Campylobacter
Candida
Chagas Disease
Chancroid
Chlamydia
Clostridium Difficile
Coronaviruses
Coxsackieviruses
Creutzfeldt-Jakobs Disease
Cryptosporidium Parvum
Cyclospora Cayetanensis
Cytomegalovirus
Ebola Virus
E. Coli
EchoVirus
Encephalitis
Enteroviruses
Epstein-Barr Virus
Giardia Lamblia
Gonorrhea
Granuloma Inguinale
Hantavirus
Helicobacter Pylori
Hepatitis: HAV NAT, HBV NAT, HBs Ag, HCV, HCV NAT,
Anti-HBc, Anti-HBs, Anti-HAV, Hepatitis Delta, HBc Ag,
HBe Ag, ALT/SGPT
Herpes Simplex Virus
Human Herpes Virus-6 (HHV-6)
Influenza Viruses
Legionella
Lyme Disease
Lymphogranuloma Venereum (LGV)
Malaria
Measles (Rubeola)
Meningitis
Table of Contents (continued)
Microsporidium
Mononucleosis
Mumps
Mycoplasma
Papillomaviruses
Parvovirus B19
Pneumonia
Polyomaviruses
Pseudomonas Aeruginosa
Rabies
Respiratory Syncytial Virus (RSV)
Rhinoviruses
Rotavirus
Rubella
Salmonellosis
Septicemia
Shigellosis
Staphylococcus Aureus
Streptococci
Syphilis
Toxoplasmosis
Trichomonas Vaginalis
Tuberculosis
Vibrio
West Nile Virus
Yersina
2. Cancer Testing
a. Overview
b. Major Cancer Types
* Prostate
* Lung
* Colon and Rectum
* Breast
* Skin
* Uterine
* Leukemia
* Oral
c. Oncogenes
O Abl/abl-bcr
O AIB1
Table of Contents (continued)
O BCL-2
O BRCA1
O CD44
O C-fos
O C-myb
O C-myc
O CYP17
O Erb-B
O HPC1
O N-myc
O P40
O P51
O P53
O PIK3CA
O PTI-1
O Ras
O Reg
O Sis
O Src
3. Genetic Diseases
a. Overview
b. Nucleic Acid Amplification
c. Chromosome Imaging
d. Genomics Technologies
e. Proteomics Technologies
f. Current Pharmacogenomic Tests
g. Future Pharmacogenomic Testing
h. Major Diseases
* Achondroplasia
* Autosomal Dominant Polycystic Kidney
Disease
* Cancer
* Cosmetogenomics
* Cystic Fibrosis
* Downs Syndrome
* Duchenne and Becker Muscular Dystrophy
* Factor V (Leiden)
* Factor IX Deficiency
* Fragile X Syndrome
Table of Contents (continued)
* Heart Disease
* Hemochomatosis
* Hemophilia
* Huntingtons Disease
* Maternal-Fetal Incompatibility
* Multiple Endocrine Neoplasia
* Phenylketonuria (PKU)
* Polycystic Kidney Disease (PKD)
* Prenatal Screening
* Retinitis Pigmentosa
* Retinoblastoma
* Sickle Cell Anemia
* Spinal Muscular Atrophy
* Vitamin B12 Metabolism
i. Social Issues and Concerns
4. Forensic Testing
a. Overview
b. Multilocus and Single Locus Probes
* Multilocus Probes
* Single Locus Probes
* PCR and RFLP
c. The FBI
d. DNA Profile Data Banks
* U.S.A.
* U.K.
e. Judicial Implementation
f. Major Crime Categories
g. Factors Contributing to the DNA Probe
Market Expansion
* Technology Availability
* Use of Hair as Evidence
h. Wildlife Forensics
5. Paternity Testing/HLA Typing
6. Other Applications
a. Disease Susceptibility Testing
b. Cardiovascular Diseases
c. Diabetes
Table of Contents (continued)
d. Alzheimers Disease
e. Periodontal Disease
f. Plasma Purification
g. Organ Transplantation
h. Water Contamination
i. Other
H. Competing/complementing
1. Monoclonal Antibodies/Immunoassays
2. RNA Probes
3. Two-Dimensional Electrophoresis
4. Flow Cytometry
VII. France Molecular Diagnostics Market
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Test Volume and Sales Forecasts,
Major Supplier Sales and Market Shares
VIII. Germany Molecular Diagnostics Market
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Test Volume and Sales Forecasts,
Major Supplier Sales and Market Shares
IX. Italy Molecular Diagnostics Market
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Test Volume and Sales Forecasts,
Major Supplier Sales and Market Shares
Table of Contents (continued)
X. Spain Molecular Diagnostics Market
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Test Volume and Sales Forecasts,
Major Supplier Sales and Market Shares
XI. U.K. Molecular Diagnostics Market
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Test Volume and Sales Forecasts,
Major Supplier Sales and Market Shares
XII. Competitive Assessments
- Abbott
- Affymetrix
- Agilent Technologies
- Applied Gene Technologies
- Arca Biopharma
- Beckman Coulter/Danaher
- Becton Dickinson
- Biokit
- bioMerieux
- Bio-Rad
- Biotest
- Cepheid
- CellMark Forensics/LabCorp
- Decode Genetics
- Diadexus
- Eiken
- Elitech Group
- Enzo
- Exact Sciences
- Fujirebio
- Grifols
- Hologic/Gen-Probe
- Illumina
Table of Contents (continued)
- Kreatech/Leica
- Li-Cor Biosciences
- Monogram Biosciences/LabCorp
- Myriad Genetics
- Ortho-Clinical Diagnostics
- Perkin Elmer/Caliper
- Proteome Sciences
- Qiagen
- Roche
- Scienion
- Sequenom
- Shimadzu
- Siemens
- Sierra Molecular
- Takara Bio
- Tecan Group
- Thermo Fisher
XIII. Appendix: Major Universities and Research Centers
Developing Molecular Diagnostic Technologies

List Of Tables

Major Companies Developing or Marketing AIDS Molecular
Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Adenovirus
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Bartonella
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Campylobacter
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Candida
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Chlamydia
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Clostridium
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Coronavirus
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Cryptosporidium
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing CMV Molecular
Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Echovirus Molecular
Diagnostic and Other Direct Identification Tests
List of Tables (continued)
Major Companies Developing or Marketing Enterovirus Molecular
Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing EBV Molecular
Diagnostic and Other Direct Identification Tests
Major Companies Developing or Marketing Giardia
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Gonorrhea
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Hantavirus
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Helicobacter
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Hepatitis
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Herpes
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Influenza
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Legionella
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Lyme
Disease Molecular Diagnostic and Other Direct
Identification Tests
List of Tables (continued)
Major Companies Developing or Marketing Measles
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Meningitis
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Mononucleosis
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Mumps
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Mycoplasma
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Pneumonia
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing RSV
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Rotavirus
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Rubella
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Salmonella
Molecular Diagnostic and Other Direct
Identification Tests
List of Tables (continued)
Major Companies Developing or Marketing Septicemia
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Shigella
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Streptococci
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Syphilis
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Toxoplasmosis
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Trichomonas
Molecular Diagnostic and Other Direct
Identification Tests
Major Companies Developing or Marketing Tuberculosis
Molecular Diagnostic and Other Direct
Identification Tests
Oncogenes Potential Application in Cancer Diagnosis
Major Companies Developing or Marketing Cancer
Molecular Diagnostic Tests
Major Companies Developing or Marketing Molecular
Diagnostic Tests For Genetic Diseases
List of Tables (continued)
France
Molecular Diagnostics Test Volume And Sales
By Major Application
France
Laboratories Performing DNA Sequencing
By Market Segment
France
Molecular Diagnostics Market
Potential Laboratory Universe by Market Segment
France
Molecular Diagnostics Test Volume
By Major Application
France
Major Infectious Disease Test Volume by Assay
France
Major Infectious Disease Test Volume by Method
France
Molecular Diagnostics Market
By Major Application
France
Molecular Diagnostics Market
Estimated Sales And Market Shares of Major Suppliers
France
Major Infectious Disease Diagnostics Market by Assay
France
AIDS Testing Market
Estimated Sales by Major Supplier
List of Tables (continued)
France
Adenovirus Testing Market
Estimated Sales by Major Supplier
France
Chlamydia Testing Market
Estimated Sales by Major Supplier
France
CMV Testing Market
Estimated Sales by Major Supplier
France
Gonorrhea Testing Market
Estimated Sales by Major Supplier
France
Hepatitis Testing Market
Estimated Sales by Major Supplier
France
Hepatitis C Testing Market
Estimated Sales by Major Supplier
France
HIV/Hepatitis Blood Screening NAT Market
Reagent Sales by Major Supplier
France
Herpes Testing Market
Estimated Sales by Major Supplier
France
Influenza Testing Market
Estimated Sales by Major Supplier
France
Meningitis Testing Market
Estimated Sales by Major Supplier
List of Tables (continued)
France
Mycoplasma Testing Market
Estimated Sales by Major Supplier
France
RSV Testing Market
Estimated Sales by Major Supplier
France
Shigella Testing Market
Estimated Sales by Major Supplier
Germany
Molecular Diagnostics Test Volume And Sales
By Major Application
Germany
Laboratories Performing DNA Sequencing
By Market Segment
Germany
Molecular Diagnostics Market
Potential Laboratory Universe by Market Segment
Germany
Molecular Diagnostics Test Volume
By Major Application
Germany
Major Infectious Disease Test Volume by Assay
Germany
Major Infectious Disease Test Volume by Method
Germany
Molecular Diagnostics Market
By Major Application
Germany
Molecular Diagnostics Market
Estimated Sales And Market Shares of Major Suppliers
List of Tables (continued)
Germany
Major Infectious Disease Diagnostics Market by Assay
Germany
AIDS Testing Market
Estimated Sales by Major Supplier
Germany
CMV Testing Market
Estimated Sales by Major Supplier
Germany
EBV Testing Market
Estimated Sales by Major Supplier
Germany
Gonorrhea Testing Market
Estimated Sales by Major Supplier
Germany
Hepatitis Testing Market
Estimated Sales by Major Supplier
Germany
Hepatitis C Testing Market
Estimated Sales by Major Supplier
Germany
HIV/Hepatitis Blood Screening NAT Market
Reagent Sales by Major Supplier
Germany
Herpes Testing Market
Estimated Sales by Major Supplier
Germany
Influenza Testing Market
Estimated Sales by Major Supplier
Germany
Meningitis Testing Market
Estimated Sales by Major Supplier
List of Tables (continued)
Germany
Mycoplasma Testing Market
Estimated Sales by Major Supplier
Germany
Pneumonia Testing Market
Estimated Sales by Major Supplier
Germany
RSV Testing Market
Estimated Sales by Major Supplier
Germany
Rotavirus Testing Market
Estimated Sales by Major Supplier
Italy
Molecular Diagnostics Test Volume And Sales
By Major Application
Italy
Laboratories Performing DNA Sequencing
By Market Segment
Italy
Molecular Diagnostics Market
Potential Laboratory Universe by Market Segment
Italy
Molecular Diagnostics Test Volume
By Major Application
Italy
Major Infectious Disease Test Volume by Assay
Italy
Major Infectious Disease Test Volume by Method
Italy
Molecular Diagnostics Market
By Major Application
List of Tables (continued)
Italy
Molecular Diagnostics Market
Estimated Sales And Market Shares of Major Suppliers
Italy
Major Infectious Disease Diagnostics Market by Assay
Italy
AIDS Testing Market
Estimated Sales by Major Supplier
Italy
CMV Testing Market
Estimated Sales by Major Supplier
Italy
Gonorrhea Testing Market
Estimated Sales by Major Supplier
Italy
Hepatitis Testing Market
Estimated Sales by Major Supplier
Italy
Hepatitis C Testing Market
Estimated Sales by Major Supplier
Italy
HIV/Hepatitis Blood Screening NAT Market
Reagent Sales by Major Supplier
Italy
Herpes Testing Market
Estimated Sales by Major Supplier
Italy
Influenza Testing Market
Estimated Sales by Major Supplier
Italy
Meningitis Testing Market
Estimated Sales by Major Supplier
List of Tables (continued)
Italy
Mycoplasma Testing Market
Estimated Sales by Major Supplier
Italy
RSV Testing Market
Estimated Sales by Major Supplier
Spain
Molecular Diagnostics Test Volume And Sales
By Major Application
Spain
Laboratories Performing DNA Sequencing
By Market Segment
Spain
Molecular Diagnostics Market
Potential Laboratory Universe by Market Segment
Spain
Molecular Diagnostics Test Volume
By Major Application
Spain
Major Infectious Disease Test Volume by Assay
Spain
Major Infectious Disease Test Volume by Method
Spain
Molecular Diagnostics Market
By Major Application
Spain
Molecular Diagnostics Market
Estimated Sales And Market Shares of Major Suppliers
Spain
Major Infectious Disease Diagnostics Market by Assay
List of Tables (continued)
Spain
AIDS Testing Market
Estimated Sales by Major Supplier
Spain
Chlamydia Testing Market
Estimated Sales by Major Supplier
Spain
CMV Testing Market
Estimated Sales by Major Supplier
Spain
Gonorrhea Testing Market
Estimated Sales by Major Supplier
Spain
Hepatitis Testing Market
Estimated Sales by Major Supplier
Spain
Hepatitis C Testing Market
Estimated Sales by Major Supplier
Spain
HIV/Hepatitis Blood Screening NAT Market
Reagent Sales by Major Supplier
Spain
Herpes Testing Market
Estimated Sales by Major Supplier
Spain
Influenza Testing Market
Estimated Sales by Major Supplier
Spain
Meningitis Testing Market
Estimated Sales by Major Supplier
List of Tables (continued)
Spain
Mycoplasma Testing Market
Estimated Sales by Major Supplier
U.K.
Molecular Diagnostics Test Volume And Sales
By Major Application
U.K.
Laboratories Performing DNA Sequencing
By Market Segment
U.K.
Molecular Diagnostics Market
Potential Laboratory Universe by Market Segment
U.K.
Molecular Diagnostics Test Volume
By Major Application
U.K.
Major Infectious Disease Test Volume by Assay
U.K.
Major Infectious Disease Test Volume by Method
U.K.
Molecular Diagnostics Market
By Major Application
U.K.
Molecular Diagnostics Market
Estimated Sales And Market Shares of Major Suppliers
U.K.
Major Infectious Disease Diagnostics Market by Assay
U.K.
AIDS Testing Market
Estimated Sales by Major Supplier
List of Tables (continued)
U.K.
Gonorrhea Testing Market
Estimated Sales by Major Supplier
U.K.
Hepatitis Testing Market
Estimated Sales by Major Supplier
U.K.
Hepatitis C Testing Market
Estimated Sales by Major Supplier
U.K.
HIV/Hepatitis Blood Screening NAT Market
Reagent Sales by Major Supplier
U.K.
Influenza Testing Market
Estimated Sales by Major Supplier
U.K.
Mycoplasma Testing Market
Estimated Sales by Major Supplier
U.K.
Pneumonia Testing Market
Estimated Sales by Major Supplier
U.K.
Shigella Testing Market
Estimated Sales by Major Supplier

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