Genome Editing: Technologies and Global Markets



Summary

Genome editing is a revolutionary technology in the biotechnology and medical fields. It is changing many related areas that form the genome editing market. The global market for genome editing was estimated at $REDACTED billion in 2017 and is expected to rapidly increase over REDACTED% to reach $REDACTED billion in2018. In the next five years, the global market is forecasted to keep a fast pace, with a compound annual growth rate (CAGR) of REDACTED%, and reach over $REDACTED billion by 2023.While all regional markets will experience fast growth at slightly different rates, the U.S. market, whichaccounted for about REDACTED% of the global genome editing market in 2017, will keep leading theindustry with growth forecasted to reach over $REDACTED billion in 2023 at an estimated CAGR of REDACTED% from 2018 through 2023.

Key Drivers of Market Growth

This report has identified several key drivers for the growth and changes in the genome editing market -
- Development of next-generation genome editing systems with improved characteristics toward therapeutic uses, including the development of the mutants or similarities of Cas9 nuclease with improved specificity and reduced off-target effect.
- Emerging applications of genome editing such as CRISPR-Cas-based in vitro diagnosis of infectious diseases.
- Need of precision medicine.
- Need of improving drug discovery process.
- Increasing demand for synthetic genes in synthetic biology.
- Investments from both public and private sectors.
- Increased R&D expenditures in related industrial sectors.
- High prevalence of genetic birth disorders.
- Concerns about genetically modified crops.

This report identifies key revenue segments for the genome editing market from various aspects. Application-based market segments include academic research, drug development, clinical therapy, non-transgenic breeding and others; product type-based market segments include editing tools, cell lines, animal models, plant breeding and therapies; editing technology-based market segments include CRISPR-Cas, TALEN, ZFN, and others such as meganucleases; and regional-based market segments include the U.S., Europe, Asia-Pacific and the Rest of World.
 

Chapter 1 Introduction
Study Goals and Objectives
Reasons for Doing This Study
Intended Audience
Scope of Report
Information Sources
Methodology
Geographic Breakdown
Analysts Credentials
BCC Custom Research
Related BCC Research Reports
Chapter 2 Summary and Highlights
Key Drivers of Market Growth
Chapter 3 Current Genome Editing Technologies
Overview
History of Genome Editing
Comparison of Genome Editing
Discovery of CRISPR-Cas9
Components of CRISPR-Cas Systems
SgRNA
Cas9 Nucleases
How CRISPR-Cas Works
Advantage of the CRISPR-Cas9 System
Popularity of CRISPR Genome Editing
Major Technological Issues
Efficiency
Specificity/Off-Target Effect
Delivery Systems
Immunogenicity Risk for Clinical Applications
A New Genome Editing System: CRISPR-Cpf1
Studies on Treating Diseases Using Genome Editing
Impact of Genome Editing
Future of CRISPR
Chapter 4 Applications of Genome Editing
Introduction
Academic Research
Drug Discovery and Development
Clinical Therapy
Non-transgenic Breeding
Diagnostics
Other Applications
Chapter 5 Market Segmentation and Forecast
Market Overview
Major Players
Market Segments by Region
Market Segments by Application
Market Segments by Technology
Market Segments by Product Type
Chapter 6 Contract Services Market Analysis
Market Overview
Major Players
Market Share and Projection
Comparison with Products Segment
Chapter 7 Research Market Analysis
Market Overview
Market Share and Projections
Patent Analysis
Publication Analysis
Research Funding Analysis
Chapter 8 Drug Development Market Analysis
Market Overview
Market Share and Forecast
Chapter 9 Agricultural Biotechnology Market Analysis
Market Overview
Market Share and Forecast
Chapter 10 Clinical Market Analysis
Market Overview
Market Share and Forecast
Comparison with Non-clinical Market
Chapter 11 Competition Landscape and Opportunities
Overview
Growth Strategies
Licensing and Agreements
Collaborations with Big Biopharmaceutical Companies
In-house R&D Program
Startup
Strategic Alliance and Joint Venture
Focus on Specific Application Areas
Venture Capital Funding
Opportunities
Chapter 12 Factors Influencing the Genome Editing Market
Introduction
Driving Forces
New Genome Editing Technologies and Related Advancements
New Applications of Genome Editing
Need for Precision Medicine
Need for Improving Drug Discovery Process
Increasing Demand for Synthetic Genes in Synthetic Biology
Investments from Both Public and Private Sectors
Increased R&D Expenditures in Related Industrial Sectors
High Prevalence of Genetic Birth Disorders
Concerns on Genetically Modified Crops
Factors Limiting the Market’s Growth
Stringent Regulatory Frameworks and Time-Consuming Approval Processes
Research Funding
Patent Disputes
Governmental Policies and Regulations
Regulatory Uncertainty on Genome Edited Crops
Ethical Issues
Chapter 13 Company Profiles
ADDGENE
AGILENT TECHNOLOGIES INC.
ALDEVRON
ALLELE BIOTECHNOLOGY
AMERICAN TYPE CULTURE COLLECTION (ATCC)
APPLIED STEMCELL INC.
ARBOR BIOTECHNOLOGIE INC.
ASTRAZENECA
ATUM (DNA2.0)
AUSTRALIAN BIORESOURCES LTD.
AXOL BIOSCIENCE LTD.
BEAM THERAPEUTICS
BIOCYTOGEN
BIO-RAD LABORATORIES INC.
BIOTOOLS CO. LTD.
BLUEBIRD BIO
B-MOGEN BIOTECHNOLOGIES INC.
CALYXT INC.
CANOPY BIOSCIENCES
CARIBOU BIOSCIENCES INC.
CASZYME
CELLECTA INC.
CELLECTICS S.A.
CIBUS
CRISPR THERAPEUTICS
DESKTOP GENETICS
EDITAS MEDICINE
GENECOPOEIA
GENEWIZ
GENSCRIPT
HORIZON DISCOVERY
INNOVATIVE GENOMICS INITIATIVE
INTELLIA THERAPEUTICS INC.
INTEGRATED DNA TECHNOLOGIES
IXCELLS BIOTECHNOLOGIES
JUNO THERAPEUTICS
LONZA
MAMMOTH BIOSCIENCES
MERCK KGAA (SIGMA-ALDRICH)
NEW ENGLAND BIOLABS
ORIGENE TECHNOLOGIES
PRECISION BIOSCIENCES INC.
RECOMBINETICS
REGENERON PHARMACEUTALS INC.
SANGAMO BIOSCIENCES
SOLENTIM INC.
SYNTHEGO
SYSTEM BIOSCIENCES
TAKARA BIO USA INC. (CLONTECH)
THERMO FISHER SCIENTIFIC
TOOLGEN INC.
TRANS GENIC INC.
TRANSOMIC TECHNOLOGIES INC.
TRANSPOSAGEN BIOPHARMACEUTICALS INC.
VERTEX PHARMACEUTICALS INC.
 


List Of Tables


Summary Table : Global Market for Genome Editing, by Region, Through 2023
Table 1 : Major Companies That Have Business Related to Genome Editing, July 2018
Table 2 : Distribution of Companies That Have Genome-Editing-Related Businesses, by Region, July 2018
Table 3 : Distribution of Companies That Have Genome-Editing-Related Businesses, by U.S. State, July 2018
Table 4 : Global Market for Genome Editing, by Region, Through 2023
Table 5 : Global Market for Genome Editing, by Application, Through 2023
Table 6 : U.S. Market for Genome Editing, by Application, Through 2023
Table 7 : European Market for Genome Editing, by Application, Through 2023
Table 8 : Asia-Pacific Market for Genome Editing, by Application, Through 2023
Table 9 : Rest of World Market for Genome Editing, by Application, Through 2023
Table 10 : Global Market for Genome Editing, by Technology, Through 2023
Table 11 : U.S. Market for Genome Editing, by Technology, Through 2023
Table 12 : European Market for Genome Editing, by Technology, Through 2023
Table 13 : Asia-Pacific Market for Genome Editing, by Technology, Through 2023
Table 14 : Rest of World Market for Genome Editing, by Technology, Through 2023
Table 15 : Global Market for Genome Editing, by Product Type, Through 2023
Table 16 : U.S. Market for Genome Editing, by Product Type, Through 2023
Table 17 : European Market for Genome Editing, by Product Type, Through 2023
Table 18 : Asia-Pacific Market for Genome Editing, by Product Type, Through 2023
Table 19 : Rest of World Market for Genome Editing, by Product Type, Through 2023
Table 20 : Major Companies That Provide Genome-Editing-Related Services, July 2018
Table 21 : Global Market for Genome Editing Services, by Region, Through 2023
Table 22 : Global Market for Genome Editing, by Product Segment, Through 2023
Table 23 : U.S. Market for Genome Editing, by Product Segment, Through 2023
Table 24 : European Market for Genome Editing, by Product Segment, Through 2023
Table 25 : Asia-Pacific Market for Genome Editing, by Product Segment, Through 2023
Table 26 : Rest of World Market for Genome Editing, by Product Segment, Through 2023
Table 27 : Global Academic Research Market for Genome Editing, by Region, Through 2023
Table 28 : Distribution of Genome Editing Patents and Patent Applications at USPTO, by Country, July 31, 2018
Table 29 : Distribution of U.S. Genome Editing Patents and Patent Applications at USPTO, by State, July 31, 2018
Table 30 : Distribution of Genome Editing Patents and Patent Applications at WIPO, by Patent Office, July 31, 2018
Table 31 : Genome Editing Patents and Patent Applications at USPTO, by Application Year, July 31, 2018
Table 32 : Genome Editing Patents and Patent Applications at WIPO, by Application Year, July 31, 2018
Table 33 : Genome Editing Patents and Patent Applications at USPTO, by Technology, July 31, 2018
Table 34 : NIH Funding for Gene/Genome Editing, by Year
Table 35 : NIH-Funded Research Grants, by Year
Table 36 : Global Drug Development Market for Genome Editing, by Region, Through 2023
Table 37 : Global Plant Breeding Market for Genome Editing, by Region, Through 2023
Table 38 : Global Market for Genome Editing, by Product Segment, Through 2023
Table 39 : U.S. Market for Genome Editing, by Product Segment, Through 2023
Table 40 : European Market for Genome Editing, by Product Segment, Through 2023
Table 41 : Asia-Pacific Market for Genome Editing, by Product Segment, Through 2023
Table 42 : Rest of World Market for Genome Editing, by Product Segment, Through 2023
 


List Of Figures

List of Figures
Summary Figure : Global Market for Genome Editing, by Region, 2017-2023
Figure 1 : Distribution Share of Companies That Have Genome-Editing-Related Businesses, by Region, July 2018
Figure 2 : Global Market for Genome Editing, by Region, 2017-2023
Figure 3 : Global Genome Editing Market Share, by Region, 2017
Figure 4 : Global Genome Editing Market Share, by Region, 2023
Figure 5 : Global Genome Editing Market Share, by Application, 2017
Figure 6 : Global Genome Editing Market Share, by Application, 2023
Figure 7 : U.S. Genome Editing Market Share, by Application, 2017
Figure 8 : U.S. Genome Editing Market Share, by Application, 2023
Figure 9 : European Genome Editing Market Share, by Application, 2017
Figure 10 : European Genome Editing Market Share, by Application, 2023
Figure 11 : Asia-Pacific Genome Editing Market Share, by Application, 2017
Figure 12 : Asia-Pacific Genome Editing Market Share, by Application, 2023
Figure 13 : Global Genome Editing Market Share, by Technology, 2017
Figure 14 : Global Genome Editing Market Share, by Technology, 2023
Figure 15 : U.S. Genome Editing Market Share, by Technology, 2017
Figure 16 : U.S. Genome Editing Market Share, by Technology, 2023
Figure 17 : European Genome Editing Market Share, by Technology, 2017
Figure 18 : European Genome Editing Market Share, by Technology, 2023
Figure 19 : Asia-Pacific Genome Editing Market Share, by Technology, 2017
Figure 20 : Asia-Pacific Genome Editing Market Share, by Technology, 2023
Figure 21 : Global Genome Editing Market Share, by Product Type, 2017
Figure 22 : Global Genome Editing Market Share, by Product Type, 2023
Figure 23 : Global Genome Editing Services Market Share, by Region, 2017
Figure 24 : Global Genome Editing Services Market Share, by Region, 2023
Figure 25 : Global Genome Editing Market Share, by Product Segment, 2017
Figure 26 : Global Genome Editing Market Share, by Product Segment, 2023
Figure 27 : Global Academic Research Market Share of Genome Editing, by Region, 2017
Figure 28 : Global Academic Research Market Share of Genome Editing, by Region, 2023
Figure 29 : Genome Editing Patents and Patent Applications Share, by Technology, July 31, 2018
Figure 30 : CRISPR Publications, by Year, August 3, 2018
Figure 31 : ZFNs Publications, by Year
Figure 32 : TALENs Publications, by Year
Figure 33 : NIH Funding for Gene/Genome Editing, by Year
Figure 34 : NIH-Funded Research Grants, by Year
Figure 35 : Global Drug Development Market Share of Genome Editing, by Region, 2017
Figure 36 : Global Drug Development Market Share of Genome Editing, by Region, 2023
Figure 37 : Global Plant Breeding Market Share of Genome Editing, by Region, 2017
Figure 38 : Global Plant Breeding Market Share of Genome Editing, by Region, 2023
Figure 39 : Global Clinical Genome Editing Market Share, by Region, 2023
Figure 40 : Global Genome Editing Market Share, by Product Segment, 2023
 


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