1.1 List of Tables 7 1.2 List of Figures 9 2 Metabolic Disorders Therapeutics Market to 2017 - Introduction 12 2.1 Overview 12 2.2 GBI Research Report Guidance 13 3 Metabolic Disorders Therapeutics Market to 2017 - Market Characterization 14 3.1 Introduction 14 3.2 Revenue Forecast for the Metabolic Disorders Therapeutics Market to 2017 15 3.2.1 Revenues 15 3.2.2 Revenue by Country 16 3.2.3 Generic Share 18 3.2.4 Annual Cost of Treatment (ACT) 19 3.3 Treatment Usage Patterns 20 3.3.1 Diseased Population 22 3.3.2 Treatment Seeking Population 23 3.3.3 Diagnosed Population 24 3.3.4 Prescription Population 25 3.4 Drivers and Restraints of the Global Metabolic Disorders Therapeutics Market 26 3.4.1 Drivers for the Metabolic Disorders Therapeutics Market 26 3.4.2 Restraints for the Metabolic Disorders Therapeutics Market 27 4 Metabolic Disorders Therapeutics Market to 2017 - Geographical Landscape 28 4.1 Revenue Analysis by Geography 28 4.2 The US 30 4.2.1 Revenue 30 4.2.2 Annual Cost of Treatment 31 4.2.3 Treatment Usage Pattern 32 4.3 Top Five Countries of Europe 37 4.3.1 Revenue 37 4.3.2 Annual Cost of Treatment 39 4.3.3 Treatment Usage Pattern 40 4.4 Japan 45 4.4.1 Revenue 45 4.4.2 Annual Cost of Treatment 46 4.4.3 Treatment Usage Pattern 47 5 Metabolic Disorders Therapeutics Market to 2017 - Diabetes Market 52 5.1 Introduction 52 5.2 Market Forecasts 52 5.2.1 Revenue by Country 54 5.2.2 Generic Share 55 5.3 Annual Cost of Treatment 56 5.4 Treatment Flow Algorithm 57 5.5 Treatment Usage Patterns 58 5.5.1 Diseased Population 59 5.5.2 Treatment Seeking Population 60 5.5.3 Diagnosed Population 61 5.5.4 Prescription Population 62 5.6 Major Marketed Products 63 5.7 Drivers and Restraints of the Diabetes Market 64 5.7.1 Drivers of the Diabetes Market 64 5.7.2 Restraints of the Diabetes Market 65 6 Metabolic Disorders Therapeutics Market to 2017 - Obesity Market 66 6.1 Introduction 66 6.2 Market Forecasts 66 6.2.1 Revenue by Country 67 6.2.2 Generic Share 68 6.3 Annual Cost of Treatment 69 6.4 Treatment Flow Algorithm 70 6.5 Treatment Usage Patterns 71 6.5.1 Diseased Population 73 6.5.2 Treatment Seeking Population 74 6.5.3 Diagnosed Population 75 6.5.4 Prescription Population 76 6.6 Major Marketed Products 77 6.7 Drivers and Restraints of the Obesity Market 77 6.7.1 Drivers of the Obesity Market 77 6.7.2 Restraints of the Obesity Market 78 7 Metabolic Disorders Therapeutics Market to 2017 - Dyslipidemia Market 79 7.1 Introduction 79 7.2 Market Forecasts 79 7.2.1 Revenue by Country 80 7.2.2 Generic Share 81 7.3 Annual Cost of Treatment 82 7.4 Treatment Flow Algorithm 83 7.5 Treatment Usage Patterns 84 7.5.1 Diseased Population 85 7.5.2 Treatment Seeking Population 86 7.5.3 Diagnosed Population 87 7.5.4 Prescription Population 88 7.6 Major Marketed Products 89 7.7 Drivers and Restraints of the Dyslipidemia Market 89 7.7.1 Drivers of the Dyslipidemia Market 89 7.7.2 Restraints of the Dyslipidemia Market 89 8 Metabolic Disorders Therapeutics Market to 2017 - Pipeline Analysis 90 8.1 Introduction 90 8.2 Diabetes: Research and Development Pipeline 92 8.2.1 Overview 92 8.2.2 Pipeline by Clinical Phases of Development 92 8.3 Obesity: Research and Development Pipeline 108 8.3.1 Overview 108 8.3.2 Pipeline by Clinical Phases of Development 108 8.4 Dyslipidemia: Research and Development Pipeline 113 8.4.1 Overview 113 8.4.2 Pipeline by Clinical Phases of Development 114 8.5 Profiles of Promising Drugs in the Diabetes Market 118 8.5.1 rhGAD65 (Diamyd) 118 8.5.2 DiaPep277 119 8.5.3 Otelixizumab 119 8.5.4 BMS-512148 (dapagliflozin) 120 8.5.5 D-Tagatose 121 8.5.6 JNJ-28431754 (canagliflozin) 121 8.5.7 Teplizumab 122 8.5.8 Lixisenatide 123 8.6 Profiles of Promising Drugs in the Obesity Market 124 8.6.1 Contrave (Buropion SR + Naltrexone) 124 8.6.2 Victoza (liraglutide) 124 8.6.3 Cametor (cetilistat) 126 8.7 Profiles of Promising Drugs in the Dyslipidemia Market 127 8.7.1 RG1658 (Dalcetrapib, JTT-705, RO4607381) 127 8.7.2 MK-0524A (Cordaptive, niacin + laropiprant) 128 8.7.3 AMR101 (LAX-101, Miraxion) 129 8.7.4 MK-0859 (anacetripib) 130 9 Metabolic Disorders Therapeutics Market to 2017 - Competitive Landscape 131 9.1 Company Profiles for Metabolic Disorders 131 9.1.1 Pfizer Inc. 131 9.1.2 Novo Nordisk 133 9.1.3 Sanofi 134 9.1.4 Takeda 136 9.1.5 Eli Lilly 137 9.1.6 GlaxoSmithKline (GSK) 138 9.1.7 Merck & Co Inc 139 9.1.8 Amylin Pharmaceuticals 141 10 Metabolic Disorders Therapeutics Market to 2017 - Strategic Consolidations 142 10.1 Mergers and Acquisitions 142 10.1.1 Segmentation by Indication 142 10.1.2 Segmentation by Deal Value 145 10.1.3 Segmentation by Geography 147 10.2 Co-Development Deals 148 10.2.1 Summary of Co-Development Deals 151 10.3 Licensing Deals 154 10.3.1 Summary of Licensing Deals 159 11 Metabolic Disorders Therapeutics Market to 2017 - Appendix 162 11.1 Market Definitions 162 11.2 Abbreviations 162 11.3 Research Methodology 164 11.3.1 Coverage 164 11.3.2 Secondary Research 164 11.3.3 Primary Research 165 11.3.4 Therapeutic Landscape 165 11.3.5 Geographical Landscape 168 11.3.6 Pipeline Analysis 168 11.3.7 Competitive Landscape 168 11.4 Expert Panel Validation 168 11.5 Contact Us 168 11.6 Disclaimer 169 11.7 Sources 169
1.1 List of Tables Table 1: Metabolic Disorders Therapeutics Market, Global, Obesity Classification by Body Mass Index (BMI), 2010 14 Table 2: Metabolic Disorders Therapeutics Market, Global, Revenue ($bn), 2002-2010 15 Table 3: Metabolic Disorders Therapeutics Market, Global, Revenue Forecasts ($bn), 2010-2017 16 Table 4: Metabolic Disorders Therapeutics Market, Global, Revenue Analysis by Geography ($bn), 2002-2010 17 Table 5: Metabolic Disorders Therapeutics Market, Global, Revenue Analysis by Geography ($bn), 2010-2017 17 Table 6: Metabolic Disorders Therapeutics Market, Global, Annual Cost of Therapy ($), 2002-2010 19 Table 7: Metabolic Disorders Therapeutics Market, Global, Annual Cost of Therapy ($), 2010-2017 19 Table 8: Metabolic Disorders Therapeutics Market, Global, Treatment Usage Patterns (million), 2002-2010 21 Table 9: Metabolic Disorders Therapeutics Market, Global, Treatment Usage Patterns (million), 2010-2017 21 Table 10: Metabolic Disorders Therapeutics Market, Global, Revenue Analysis by Geography ($bn), 2002-2010 28 Table 11: Metabolic Disorders Therapeutics Market, Global, Revenue Analysis by Geography ($bn), 2010-2017 29 Table 12: Metabolic Disorders Therapeutics Market, The US, Revenue ($bn), 2002-2010 30 Table 13: Metabolic Disorders Therapeutics Market, The US, Revenue Forecasts ($bn), 2010-2017 30 Table 14: Metabolic Disorders Therapeutics Market, The US, Annual Cost of Therapy ($), 2002-2010 31 Table 15: Metabolic Disorders Therapeutics Market, The US, Annual Cost of Therapy ($), 2010-2017 31 Table 16: Metabolic Disorders Therapeutics Market, The US, Treatment Usage Pattern (million), 2002-2010 32 Table 17: Metabolic Disorders Therapeutics Market, The US, Treatment Usage Pattern (million), 2010-2017 33 Table 18: Metabolic Disorders Therapeutics Market, Top Five Countries of Europe, Revenue ($bn), 2002-2010 37 Table 19: Metabolic Disorders Therapeutics Market, Top Five Countries of Europe, Revenue Forecasts ($bn), 2010-2017 38 Table 20: Metabolic Disorders Therapeutics Market, Top Five Countries of Europe, Annual Cost of Therapy ($), 2002-2010 39 Table 21: Metabolic Disorders Therapeutics Market, Top Five Countries of Europe, Annual Cost of Therapy ($), 2010-2017 39 Table 22: Metabolic Disorders Therapeutics Market, Top Five Countries of Europe, Treatment Usage Pattern (million), 2002-2010 40 Table 23: Metabolic Disorders Therapeutics Market, Top Five Countries of Europe, Treatment Usage Pattern (million), 2010-2017 41 Table 24: Metabolic Disorders Therapeutics Market, Japan, Revenue ($bn), 2002-2010 45 Table 25: Metabolic Disorders Therapeutics Market, Japan, Revenue Forecasts ($bn), 2010-2017 45 Table 26: Metabolic Disorders Therapeutics Market, Japan, Annual Cost of Therapy ($), 2002-2010 46 Table 27: Metabolic Disorders Therapeutics Market, Japan, Annual Cost of Therapy ($), 2010-2017 46 Table 28: Metabolic Disorders Therapeutics Market, Japan, Treatment Usage Pattern (million), 2002-2010 47 Table 29: Metabolic Disorders Therapeutics Market, Japan, Treatment Usage Pattern (million), 2010-2017 48 Table 30: Diabetes Therapeutics Market, Global, Revenue ($bn), 2002-2010 53 Table 31: Diabetes Therapeutics Market, Global, Revenue Forecasts ($bn), 2010-2017 53 Table 32: Diabetes Therapeutics Market, Global, Revenue Analysis by Geography ($bn), 2002-2010 54 Table 33: Diabetes Therapeutics Market, Global, Revenue Analysis by Geography ($bn), 2010-2017 55 Table 34: Diabetes Therapeutics Market, Global, Annual Cost of Therapy ($), 2002-2010 56 Table 35: Diabetes Therapeutics Market, Global, Annual Cost of Therapy ($), 2010-2017 56 Table 36: Diabetes Therapeutics Market, Global, Treatment Usage Pattern (million), 2002-2010 58 Table 37: Diabetes Therapeutics Market, Global, Treatment Usage Pattern (million), 2010-2017 59 Table 38: Diabetes Therapeutics Market, Global, Major Drugs, 2009-2010 64 Table 39: Obesity Therapeutics Market, Global, Revenue ($bn), 2002-2010 66 Table 40: Obesity Therapeutics Market, Global, Revenue Forecasts ($bn), 2010-2017 67 Table 41: Obesity Therapeutics Market, Global, Revenue Analysis by Geography ($bn), 2002-2010 67 Table 42: Obesity Therapeutics Market, Global, Revenue Analysis by Geography ($bn), 2010-2017 68 Table 43: Obesity Therapeutics Market, Global, Annual Cost of Therapy ($), 2002-2010 69 Table 44: Obesity Therapeutics Market, Global, Annual Cost of Therapy ($), 2010-2017 69 Table 45: Obesity Therapeutics Market, Global, Treatment Usage Pattern (million), 2002-2010 72 Table 46: Obesity Therapeutics Market, Global, Treatment Usage Pattern (million), 2010-2017 72 Table 47: Obesity Therapeutics Market, Global, Major Drugs, 2002-2017 77 Table 48: Dyslipidemia Therapeutics Market, Global, Revenue ($bn), 2002-2010 79 Table 49: Dyslipidemia Therapeutics Market, Global, Revenue Forecasts ($bn), 2010-2017 80 Table 50: Dyslipidemia Therapeutics Market, Global, Revenue Analysis by Geography ($bn), 2002-2010 80 Table 51: Dyslipidemia Therapeutics Market, Global, Revenue Analysis by Geography ($bn), 2010-2017 81 Table 52: Dyslipidemia Therapeutics Market, Global, Annual Cost of Therapy ($), 2002-2010 82 Table 53: Dyslipidemia Therapeutics Market, Global, Annual Cost of Therapy ($), 2010-2017 82 Table 54: Dyslipidemia Therapeutics Market, Global, Treatment Usage Pattern (million), 2002-2010 84 Table 55: Dyslipidemia Therapeutics Market, Global, Treatment Usage Pattern (million), 2010-2017 85 Table 56: Dyslipidemia Therapeutics Market, Global, Major Drugs, 2002-2017 89 Table 57: Diabetes Therapeutics Market, Global, Pre-Clinical/Discovery Phase, 2010 93 Table 58: Diabetes Therapeutics Market, Global, Phase I, 2010 97 Table 59: Diabetes Therapeutics Market, Global, Phase II, 2010 101 Table 60: Diabetes Therapeutics Market, Global, Phase III, 2010 105 Table 61: Diabetes Therapeutics Market, Global, NDA/Filed Molecules, 2010 107 Table 62: Obesity Therapeutics Market, Global, Pre-Clinical/Discovery Phase, 2010 109 Table 63: Obesity Therapeutics Market, Global, Phase I, 2010 111 Table 64: Obesity Therapeutics Market, Global, Phase II, 2010 112 Table 65: Obesity Therapeutics Market, Global, Phase III, 2010 112 Table 66: Obesity Therapeutics Market, Global, NDA/Filed Molecules, 2010 112 Table 67: Dyslipidemia Therapeutics Market, Global, Pre-Clinical/Discovery Phase, 2010 114 Table 68: Dyslipidemia Therapeutics Market, Global, Phase I, 2010 115 Table 69: Dyslipidemia Therapeutics Market, Global, Phase II, 2010 116 Table 70: Dyslipidemia Therapeutics Market, Global, Phase III, 2010 117 Table 71: Metabolic Disorders Therapeutics Market, M&A Deals, 2009-2011 143 Table 72: Metabolic Disorders Therapeutics Market, M&A Top Deals by Value ($m), 2009-2011 146 Table 73: Metabolic Disorders Therapeutics Market, Co-Development, By Geography, 2009-2011 149 Table 74: Metabolic Disorders Therapeutics Market, Licensing Deals, By Geography, 2009-2011 155
1.2 List of Figures Figure 1: Metabolic Disorders Therapeutics Market, Global, Revenue Forecasts ($bn), 2002-2017 14 Figure 2: Metabolic Disorders Therapeutics Market, Global, Revenue Analysis by Geography ($bn), 2002-2017 15 Figure 3: Metabolic Disorders Therapeutics Market, Global, Generic Share, 2010 and 2017 17 Figure 4: Metabolic Disorders Therapeutics Market, Global, Annual Cost of Therapy ($), 2002-2017 18 Figure 5: Metabolic Disorders Therapeutics Market, Global, Treatment Usage Patterns (million), 2002-2017 19 Figure 6: Metabolic Disorders Therapeutics Market, Global, Diseased Population (million), 2002-2017 21 Figure 7: Metabolic Disorders Therapeutics Market, Global, Treatment Seeking Population (million), 2002-2017 22 Figure 8: Metabolic Disorders Therapeutics Market, Global, Diagnosis Population (million), 2002-2017 23 Figure 9: Metabolic Disorders Therapeutics Market, Global, Prescription Population (million), 2002-2017 24 Figure 10: Metabolic Disorders Therapeutics Market, Global, Revenue Analysis by Geography ($bn), 2002-2017 27 Figure 11: Metabolic Disorders Therapeutics Market, The US, Revenue Forecasts ($bn), 2002-2017 29 Figure 12: Metabolic Disorders Therapeutics Market, The US, Annual Cost of Therapy ($), 2002-2017 30 Figure 13: Metabolic Disorders Therapeutics Market, The US, Treatment Usage Pattern (million), 2002-2017 31 Figure 14: Metabolic Disorders Therapeutics Market, The US, Diseased Population (million), 2002-2017 32 Figure 15: Metabolic Disorders Therapeutics Market, The US, Treatment Seeking Population (million), 2002-2017 33 Figure 16: Metabolic Disorders Therapeutics Market, The US, Diagnosed Population (million), 2002-2017 34 Figure 17: Metabolic Disorders Therapeutics Market, The US, Prescription Population (million), 2002-2017 35 Figure 18: Metabolic Disorders Therapeutics Market, Top Five Countries of Europe, Revenue Forecasts ($bn), 2002-2017 36 Figure 19: Metabolic Disorders Therapeutics Market, Top Five Countries of Europe, Annual Cost of Therapy ($), 2002-2017 38 Figure 20: Metabolic Disorders Therapeutics Market, Top Five Countries of Europe, Treatment Usage Pattern (million), 2002-2017 39 Figure 21: Metabolic Disorders Therapeutics Market, Top Five Countries of Europe, Diseased Population (million), 2002-2017 40 Figure 22: Metabolic Disorders Therapeutics Market, Top Five Countries of Europe, Treatment Seeking Population (million), 2002-2017 41 Figure 23: Metabolic Disorders Therapeutics Market, Top Five Countries of Europe, Diagnosed Population (million), 2002-2017 42 Figure 24: Metabolic Disorders Therapeutics Market, Top Five Countries of Europe, Prescription Population (million), 2002-2017 43 Figure 25: Metabolic Disorders Therapeutics Market, Japan, Revenue Forecasts ($bn), 2002-2017 44 Figure 26: Metabolic Disorders Therapeutics Market, Japan, Annual Cost of Therapy ($), 2002-2017 45 Figure 27: Metabolic Disorders Therapeutics Market, Japan, Treatment Usage Pattern (million), 2002-2017 46 Figure 28: Metabolic Disorders Therapeutics Market, Japan, Diseased Population (million), 2002-2017 47 Figure 29: Metabolic Disorders Therapeutics Market, Japan, Treatment Seeking Population (million), 2002-2017 48 Figure 30: Metabolic Disorders Therapeutics Market, Japan, Diagnosed Population (million), 2002-2017 49 Figure 31: Metabolic Disorders Therapeutics Market, Japan, Prescription Population (million), 2002-2017 50 Figure 32: Diabetes Therapeutics Market, Global, Revenue Forecasts ($bn), 2002-2017 52 Figure 33: Diabetes Therapeutics Market, Global, Revenue Analysis by Geography ($bn), 2002-2017 53 Figure 34: Diabetes Therapeutics Market, Global, Generic Share, 2010 and 2017 54 Figure 35: Diabetes Therapeutics Market, Global, Annual Cost of Therapy ($), 2002-2017 55 Figure 36: Diabetes Therapeutics Market, Treatment Flow Algorithm 56 Figure 37: Diabetes Therapeutics Market, Global, Treatment Usage Pattern (million), 2002-2017 57 Figure 38: Diabetes Therapeutics Market, Global, Diseased Population (million), 2002-2017 58 Figure 39: Diabetes Therapeutics Market, Global, Treatment Seeking Population (million), 2002-2017 59 Figure 40: Diabetes Therapeutics Market, Global, Diagnosed Population (million), 2002-2017 60 Figure 41: Diabetes Therapeutics Market, Global, Prescription Population (million), 2002-2017 61 Figure 42: Diabetes Therapeutics Market, Global, Major Companies, Revenue ($bn), 2009-2010 62 Figure 43: Obesity Therapeutics Market, Global, Revenue Forecasts ($bn), 2002-2017 65 Figure 44: Obesity Therapeutics Market, Global, Revenue Analysis by Geography ($bn), 2002-2017 66 Figure 45: Obesity Therapeutics Market, Global, Generic Share, 2010 and 2017 67 Figure 46: Obesity Therapeutics Market, Global, Annual Cost of Therapy ($), 2002-2017 68 Figure 47: Obesity Therapeutics Market, Treatment Flow Algorithm - 1 69 Figure 48: Obesity Therapeutics Market, Treatment Flow Algorithm - 2 69 Figure 49: Obesity Therapeutics Market, Global, Treatment Usage Pattern (million), 2002-2017 70 Figure 50: Obesity Therapeutics Market, Global, Diseased Population (million), 2002-2017 72 Figure 51: Obesity Therapeutics Market, Global, Treatment Seeking Population (million), 2002-2017 73 Figure 52: Obesity Therapeutics Market, Global, Diagnosed Population (million), 2002-2017 74 Figure 53: Obesity Therapeutics Market, Global, Prescription Population (million), 2002-2017 75 Figure 54: Dyslipidemia Therapeutics Market, Global, Revenue Forecasts ($bn), 2002-2017 78 Figure 55: Dyslipidemia Therapeutics Market, Global, Revenue Analysis by Geography ($bn), 2002-2017 79 Figure 56: Dyslipidemia Therapeutics Market, Global, Generic Share, 2010 and 2017 80 Figure 57: Dyslipidemia Therapeutics Market, Global, Annual Cost of Therapy ($), 2002-2017 81 Figure 58: Dyslipidemia Therapeutics Market, Treatment Flow Algorithm 82 Figure 59: Dyslipidemia Therapeutics Market, Global, Treatment Usage Pattern (million), 2002-2017 83 Figure 60: Dyslipidemia Therapeutics Market, Global, Diseased Population (million), 2002-2017 84 Figure 61: Dyslipidemia Therapeutics Market, Global, Treatment Seeking Population (million), 2002-2017 85 Figure 62: Dyslipidemia Therapeutics Market, Global, Diagnosed Population (million), 2002-2017 86 Figure 63: Dyslipidemia Therapeutics Market, Global, Prescription Population (million), 2002-2017 87 Figure 64: Metabolic Disorders Therapeutics Market, Global, R&D Pipeline by Indication (%), 2010 89 Figure 65: Metabolic Disorders Therapeutics Market, Global, R&D Pipeline by Phase (%), 2010 90 Figure 66: Diabetes Therapeutics Market, Global, R&D Pipeline by Phase (%), 2010 91 Figure 67: Obesity Therapeutics Market, Global, R&D Pipeline by Phase (%), 2010 107 Figure 68: Dyslipidemia Therapeutics Market, Global, R&D Pipeline by Phase (%), 2010 112 Figure 69: Metabolic Disorders Therapeutics Market, Company Shares, 2010 130 Figure 70: Metabolic Disorders Therapeutics Market, Pfizer Inc., SWOT Analysis, 2010 131 Figure 71: Metabolic Disorders Therapeutics Market, Novo Nordisk, SWOT Analysis, 2010 133 Figure 72: Metabolic Disorders Therapeutics Market, Sanofi, SWOT Analysis, 2010 134 Figure 73: Metabolic Disorders Therapeutics Market, Takeda, SWOT Analysis, 2010 135 Figure 74: Metabolic Disorders Therapeutics Market, Eli Lilly, SWOT Analysis, 2010 137 Figure 75: Metabolic Disorders Therapeutics Market, GSK, SWOT Analysis, 2010 138 Figure 76: Metabolic Disorders Therapeutics Market, Merck & Co. Inc., SWOT Analysis, 2010 139 Figure 77: Metabolic Disorders Therapeutics Market, Amylin Pharmaceuticals, SWOT Analysis, 2010 140 Figure 78: Metabolic Disorders Therapeutics Market, M&A, by Indication, 2010 141 Figure 79: Metabolic Disorders Therapeutics Market, M&A Deals by Deal Value ($m), 2009-2011 144 Figure 80: Metabolic Disorders Therapeutics Market, M&A Deals, By Geography, 2009-2011 146 Figure 81: Metabolic Disorders Therapeutics Market, Co-Development, By Indications, 2009-2011 147 Figure 82: Metabolic Disorders Therapeutics Market, Licensing Deals, By Geography, 2009-2011 158 Figure 83: GBI Research Market Forecasting Model 166
Companies Mentioned
Pfizer Inc. Novo Nordisk Sanofi Takeda Eli Lilly GlaxoSmithKline (GSK) Merck & Co Inc Amylin Pharmaceuticals |