Frequency of Sequencer Runs

Next-Generation Systems

Capillary Systems

Outsourcing

Output, Read Lengths, Single- or Paired-Ends

Next-Generation Systems

Capillary Systems

Targeted Enrichment Systems Being Used

CHAPTER FIVE: PREFERENCES AND EVALUATIONS

Exhibit ES-1: Distribution of Survey Respondent Labs, by Type

Exhibit 1: Regional Distribution of Labs (North America, Europe, Asia-Pacific, R.O.W)

Exhibit 2: Industrial Distribution of Labs (Academia, Hospital, Indep. Research/Non-profit, Contract Rsch/ Svcs, Gov't, Other)

Exhibit 3: Industrial Distribution of Labs, by Region (# of Labs)

Exhibit 4: Industrial Distribution of Labs, Cross-Referenced by Region (% of Labs)

Exhibit 5: Major Function(s) of Labs (Core Lab, Service Provider, Research, Genome Center, Diagnostics, Teaching, Bioinformatics, Overall)

Exhibit 6: Major Function(s) of Labs, by Region (# of Labs)

Exhibit 7: Major Function(s) of Labs, Cross Referenced by Region (% of Labs)

Exhibit 8: Distribution of Total Number of Sequencers in Respondent Labs

Exhibit 9: Distribution of Number of Next-Generation Sequencers in Labs

Exhibit 10: Distribution of Number of Capillary/ Gel Sequencers in Labs

Exhibit 11: Distribution of Number of Sequencers Elsewhere in Organization

Exhibit 12: Brands/ Types of Sequencers Owned Overall in Respondent Labs(Next gen, ABI/Life Tech., ABI Capillary/ Gel, Illumina, 454, ABI SOLiD, No sequencer)

Exhibit 13: Average Number of Sequencers in Respondent Labs, by Brand/ Type

Exhibit 14: Main Types of Samples Being Sequenced in Labs (Human, Bacteria, Plant, Agricultural, Animals, Variety, Other)

Exhibit 15: Distribution of Positions/ Roles of Respondents

Exhibit 16: Installed Base of Respondent Labs, by Model

Exhibit 17: Distribution of ABI SOLiD System Versions in Respondents' Labs

Exhibit 18: Installed Base of Models in Labs, by Brand/ Type of System(s) Owned (# of Systems)

Exhibit 19: Installed Base of Models in Labs, Cross-Referenced by Brand/ Type of System(s) Owned (% of Systems)

Exhibit 20: Installed Base of Labs by Brand/ Type of System Owned, Cross-Referenced by Model (% of Systems)

Exhibit 21: Distribution of Number of Sequencers, by Number of Next-Generation Systems vs Number of Capillary Systems (# of Labs)

Exhibit 22: Distribution of Number of Sequencers, by Number of Next-Generation Systems vs Number of Capillary Systems (% of Labs)

Exhibit 23: Distribution of Number of Sequencers, by Number of Capillary Systems vs Number of Next-Generation Systems (% of Labs)

Exhibit 24: Average Number of Systems Installed in Respondent Labs, by Region (N. America, Europe, Asia, R.O.W.)

Exhibit 25: Sequencer Models in Respondent Labs, by Region (# of Systems)

Exhibit 26: Sequencer Models in Respondent Labs, by Region (% of Systems)

Exhibit 27: Next-Gen Sequencer Models in Respondent Labs, by Region (# of Systems)

Exhibit 28: Next-Gen Sequencer Models in Respondent Labs, by Region (% of Systems)

Exhibit 29: Capillary and Gel Sequencer Models in Labs, by Region (# of Systems)

Exhibit 30: Capillary and Gel Sequencer Models in Labs, by Region (% of Systems)

Exhibit 31: Average Number of Sequencers Installed by Industry/ Segment (Academic, Hospital, Indep. Rsch/ Non-profit, Contract Research/ Svcs, Government, Other)

Exhibit 32: Industrial Distribution of Systems, by Brand/ Type (# of Systems)

Exhibit 33: Industrial Distribution of Systems, by Brand/ Type (% of Systems)

Exhibit 34: Brand/ Type of Sequencer System Installed, Cross-Referenced by Industry/ Segment (% of Systems)

Exhibit 35: Number of Next-Generation Systems in Labs Owning, by Industry/Segment (Academic, Hospital, Indep. Rsch/ Non-profit, Contract Rsch/ Svcs, Gov't, Other)

Exhibit 36: Industrial Distribution of Next-Generation Sequencers, by Model (# of Systems)

Exhibit 37: Industrial Distribution of Next-Generation Sequencers, by Model (% of Systems)

Exhibit 38: Next-Generation Models in Respondent Labs, by Industry/ Segment (% of Systems)

Exhibit 39: Capillary/Gel Systems Installed in Lab Owning, by Industry/Segment (Academic, Hospital, Indep. Rsch/ Non-profit, Contract Rsch/ Svcs, Gov't, Other)

Exhibit 40: Industrial Distribution of Capillary/Gel Sequencers, by Model (# of Systems)

Exhibit 41: Industrial Distribution of Capillary/Gel Sequencers, by Model (% of Systems)

Exhibit 42: Capillary/ Gel Sequencer Models in Labs, by Industry/ Segment (% of Systems)

Exhibit 43: Average Number of Systems Installed by Laboratory Function

Exhibit 44: Distribution of Systems by Lab Function, by Brand/ Type (# of Systems)

Exhibit 45: Distribution of Systems by Lab Function, by Brand/ Type (% of Systems)

Exhibit 46: Brand/Type of System Installed, Cross-Referenced by Lab Function (% of Systems)

Exhibit 47: Average Number of Next-Generation Systems in Labs Owning, by Lab Function

Exhibit 48: Next Generation Models in Respondent's Labs, by Lab Function (# of Systems)

Exhibit 49: Distribution of Next-Generation Systems by Lab Function, Cross-Referenced by Model (% of Systems)

Exhibit 50: Next Generation Models in Respondent Labs, by Lab Function (% of Systems)

Exhibit 51: Average Number of Capillary/ Gel Systems in Labs Owning, By Lab Function

Exhibit 52: Distribution of Capillary/ Gel Sequencers by Lab Function, by Model (# of Systems)

Exhibit 53: Distribution of Capillary/ Gel Sequencers by Lab Function, by Model (% of Systems)

Exhibit 54: Capillary/ Gel Sequencer Models in Labs, by Lab Function (% of Systems)

Exhibit 55: Age of Next-Generation and Capillary Systems Installed in Labs, Q1 2000 - Q4 2004

Exhibit 56: Age of Next-Generation and Capillary Systems Installed in Labs, Q1 2005 - Q3 2010

Exhibit 57: Age of Next-Generation Systems in Respondent Labs by Model, Q3 2005 - Q3 2010

CHAPTER FOUR: APPLICATIONS AND USAGE TRENDS

Exhibit 58: Distribution of Runs/ Libraries by Application, by Brand/ Type (% of Samples)

Exhibit 59: Applications Expected to Increase the Most

Exhibit 60: Applications Expected to Increase the Most, for Next-Generation Systems

Exhibit 61: Applications Expected to Increase the Most, Capillary/Gel System Owners

Exhibit 62: Applications Expected to Increase the Most, by Brand/ Type Owned (# of Labs)

Exhibit 63: Applications Expected to Increase the Most, by Brand/ Type Owned (% of Labs)

Exhibit 64: Frequency that Next-Generation Systems are Running (# of Systems)

Exhibit 65: Frequency that Next-Generation Systems are Running (% of Systems)

Exhibit 66: Distribution of Number of Plates Run per Week, for Capillary Systems

Exhibit 67: Overall Distribution of Outsourcing of Sequencing

Exhibit 68: Regional Distribution of Outsourcing of Sequencing (# of Labs)

Exhibit 69: Regional Distribution of Outsourcing of Sequencing (% of Labs)

Exhibit 70: Distribution of Reasons for Outsourcing of Sequencing

Exhibit 71: Distribution of Typical Read Lengths of Capillary Systems

Exhibit 72: Distribution of Targeted Enrichment Systems Used by Labs

Exhibit 73: Distribution of Systems Used to Check Concentration, Size, Quality

Exhibit 74: Labs' Most Important Criteria for Sequencer Purchase

Exhibit 75: Labs' Most Important Criteria for Sequencer Purchase, by Brand/ Type Owned (# of Labs)

Exhibit 76: Labs' Most Important Criteria for Sequencer Purchase, by Brand/ Type Owned (% of Labs)

Exhibit 77: Labs' Satisfaction Ratings of System Features by Brand/ Type (1-very dissatisf., 2-somewhat dissatisf., 3-avg. or indifferent, 4-slightly satisf., 5-very satisf.)

Exhibit 78: Satisfaction Ratings of Next-Generation System Features by Brand (1-very dissatisf., 2-somewhat dissatisf., 3-avg. or indifferent, 4-slightly satisf., 5-very satisf.)

Exhibit 79: Feature or Process Most Wanted to Change or Improve, by Brand/ Type (# of Labs)

Exhibit 80: Feature(s) or Process Most Wanted to Change or Improve, by Brand/Type (% of Labs)

Exhibit 81: Main Bottleneck(s) in Sequencing Process (# of Labs)

Exhibit 82: Main Bottleneck(s) in Sequencing Process (% of Labs)

Exhibit 83: Difficulty of Data Analysis, by Brand/ Type (# of Labs)

Exhibit 84: Difficulty of Data Analysis, by Brand/ Type (% of Labs)

Exhibit 85: Difficulty of Data Management, by Brand/ Type (# of Labs)

Exhibit 86: Difficulty of Data Management, by Brand/ Type (% of Labs)

Exhibit 87: Time Frame for Sequencer Purchase Plan(s)

Exhibit 88:Time Frame(s) for Sequencer Purchase Plan(s) (# and % of Systems)

Exhibit 89: Time Frame(s) for Sequencer Purchase Plan(s), by Brand/ Type Owned (# of Systems)

Exhibit 90: Time Frame(s) for Sequencer Purchase Plan(s), by Brand/ Type Owned (% of Systems)

Exhibit 91: Time Frame(s) for Sequencer Purchase Plan(s), by Industry/ Segment (# of Systems)

Exhibit 92: Time Frame(s) for Sequencer Purchase Plan(s), by Industry/ Segment (% of Systems)

Exhibit 93: Time Frame(s) for Sequencer Purchase Plan(s), by Lab Function (# of Systems)

Exhibit 94: Time Frame(s) for Sequencer Purchase Plan(s), by Industry/ Segment (% of Systems)

Exhibit 95: Time Frame(s) for Sequencer Purchase Plan(s), by Region (# of Systems)

Exhibit 96: Time Frame(s) for Sequencer Purchase Plan(s), by Region (% of Systems)

Exhibit 97: Sequencer Models Likely to Consider for Future Purchase

Exhibit 98: Sequencer Models Likely to Consider, by Brand/ Type Owned (# of Labs)

Exhibit 99: Sequencer Models Likely to Consider, by Brand/ Type Owned (% of Labs)

Exhibit 100: Sequencer Models Likely to Consider, Capillary/ Gel System-Only Owners

Exhibit 101: Sequencer Models Likely to Consider, Next-Generation System-Only Owners

Exhibit 102: Sequencer Models Likely to Consider, by Industry/ Segment (# of Labs)

Exhibit 103: Sequencer Models Likely to Consider, by Industry/ Segment (% of Labs)

Exhibit 104: Sequencer Models Likely to Consider, by Lab Function (# of Labs)

Exhibit 105: Sequencer Models Likely to Consider, by Lab Function (% of Labs)

Exhibit 106: Sequencer Models Likely to Consider, by Region (# of Labs)

Exhibit 107: Sequencer Models Likely to Consider, by Region (% of Labs)

Exhibit 108: Barriers or Issues Hindering 2nd and 3rd Generation Sequencers (# of Labs)

Exhibit 109: Barriers or Issues Hindering 2nd and 3rd Generation Sequencers (% of Labs)